The search for effective food ingredient in cancer prevention to control epigenetics
Project/Area Number |
25460781
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Epidemiology and preventive medicine
|
Research Institution | Chubu University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
NASU Tamie 中部大学, 生命健康科学部, 教授 (10020794)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | エピジェネティクス / ガン / 食品 / メチル化 |
Outline of Final Research Achievements |
Modification of DNA are found in the process of malignant transformation from normal cells in many cancers. If this phenomenon in the regulatory site of the tumor suppressor gene occurs, it is believed that malignant transformation is likely to occur. In the present study, the chemical substance of the food component to cause the re-expression and modification of the tumor suppressor gene was to explore, but a new material was not found. Though the benign tumor of a model mouse of the multi-stage carcinogenesis was used, it was not observed these effect.
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Report
(4 results)
Research Products
(5 results)