| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
The dietary intake of ω3 polyunsaturated fatty acids(PUFA) were increased in 10 years compared to those of ω6 PUFA. Serum eicosapentanoic acid to arachidonic acid ratio (EPA/AA ratio) were significantly higher in fishing community than in farming community, because people in fishing community eat fish oil more than those in farming community. Serum EPA or DHA levels were positively correlate to the dietary intake of ω3 PUFA, but there wasn’t significant association between serum AA levels and the dietary intake of ω6 PUFA. Therefore we revealed that it is important to eat muchω3 PUFA to elevate serum EPA/AA ratios. In cross sectional study, we demonstrated that serum EPA/AA ratio was strongly associated with microalbuminuria. But serum EPA/AA ratio at baseline were not predicted of the progression of microalbuminuria in prospective study.
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