Molecular epidemiology of viral gastroenteritis, one of zoonotic diseases, in Asia
Project/Area Number |
25460791
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Hygiene and public health
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Research Institution | The University of Tokyo |
Principal Investigator |
OKITSU Shoko 東京大学, 医学(系)研究科(研究院), 研究員 (10082215)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Keywords | ウイルス / 下痢症 / 人獣共通感染症 / 国際情報交換 / アジア / タイ / 感染症 |
Outline of Final Research Achievements |
Several types of viruses were detected in the diarrheal stool samples from infants and children with acute gastroenteritis, who visited the pediatric clinics in Japan, 2009 to 2014. The study demonstrated that the most prevalent viruses were norovirus GII and rotavirus. The most common genotype of norovirus was GII.4, and GII.4 variants were changing in the period study. Detection of cosavirus, family Picornaviridae, was reported for the first time in a diarrheal stool sample, in Japan. My data demonstrated that cosavirus is caused diarrhea in the patient, and the detected virus strain belongs to a new genotype in the cosavirus A. Furthermore, the study indicated that the virus infection is one of the zoonotic diseases. Aichivirus C was supposed to be diarrheal pathogen in pigs. This study demonstrated that the Aichivirus C was circulated in swine populations in Japan and Thailand and may not related to the pathogenesis in pigs.
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Report
(4 results)
Research Products
(85 results)
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[Journal Article] Human rhinovirus infections in hospitalized children: clinical, epidemiological and virological features.2016
Author(s)
Tran DN, Trinh QD, Pham NT, Pham TM, Ha MT, Nguyen TQ, Okitsu S, Shimizu H, Hayakawa S, Mizuguchi M, Ushijima H.
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Journal Title
Epidemiol Infect.
Volume: 144
Issue: 2
Pages: 346-54
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Antibiotic Resistance of <i>Campylobacter jejuni</i> and <i>C. coli</i> Isolated from Children with Diarrhea in Thailand and Japan2016
Author(s)
Pham NT, Thongprachum A, Tran DN, Nishimura S, Shimizu-Onda Y, Trinh QD, Khamrin P, Ukarapol N, Kongsricharoern T, Komine-Aizawa S, Okitsu S, Maneekarn N, Hayakawa S, Ushijima H.
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Journal Title
Japanese Journal of Infectious Diseases
Volume: 69
Issue: 1
Pages: 77-79
DOI
NAID
ISSN
1344-6304, 1884-2836
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Cosavirus (family Picornaviridae) in pigs in Thailand and Japan2016
Author(s)
Okitsu S, Khamrin P, Hanaoka N, Thongprachum A, Takanashi S, Fujimoto T, Mizuguchi M, Shimizu H, Hayakawa S, Maneekarn N, Ushijima H
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Journal Title
Arch Virol
Volume: 161
Issue: 1
Pages: 159-163
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Loop-Mediated Isothermal Amplification (LAMP) for Detection of <i>Campylobacter jejuni</i> and <i>C. coli</i> in Thai Children with Diarrhea2015
Author(s)
Pham NTK, Trinh QD, Khamrin P, Ukarapol N, Kongsricharoern T, Yamazaki W, Okitsu S, Maneekarn N, Hayakawa S, Ushijima H
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Journal Title
Japanese Journal of Infectious Diseases
Volume: 68
Issue: 5
Pages: 432-433
DOI
NAID
ISSN
1344-6304, 1884-2836
Related Report
Peer Reviewed / Open Access
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[Journal Article] Sensitive and Rapid Detection of <i>Campylobacter</i> Species from Stools of Children with Diarrhea in Japan by the Loop-Mediated Isothermal Amplification Method2014
Author(s)
Ushijima H, Nishimura S, Thongprachum A, Shimizu-Onda Y, Tran DN, Pham NTK, Takanashi S, Dey SK, Okitsu S, Yamazaki W, Mizuguchi M, Hayakawa S
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Journal Title
Japanese Journal of Infectious Diseases
Volume: 67
Issue: 5
Pages: 374-378
DOI
NAID
ISSN
1344-6304, 1884-2836
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Detection and molecular characterization of human cosavirus in a pediatric patient with acute gastroenteritis, Japan2014
Author(s)
Okitsu S, Khamrin P, Thongprachum A, Nishimura S, Kalesaran AFC, Takanashi S, Shimizu H, Hayakawa S, Mizuguchi M, Ushijima H
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Journal Title
Infect Genet Evol
Volume: 28
Pages: 125-129
DOI
Related Report
Peer Reviewed
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[Presentation] Circulating rotavirus in hospitalized pediatric patients, with the predominance of G1P[8]DS-1-like human rotavirus in Manado, Indonesia2014
Author(s)
Kalesaran AFC, Thongprachum A, Pangemanan DHC, Takanashi S, Okitsu S, Hayakawa S, Warouw SM, Mizuguchi M, Ushijima H
Organizer
International Meeting on Emerging Diseases and Suiveillance
Place of Presentation
Hilton Vienna (オーストリア、ウイーン市)
Year and Date
2014-10-31 – 2014-11-03
Related Report
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[Presentation] Molecular epidemiology and genetic analyses of norovirus in Japan, 2006-20142014
Author(s)
Thongprachum A, Chan-it W, Takanashi S, Okitsu S, Kobayashi M, Nishimura S, Kikuta H, Yamamoto A, Sugita K, Baba T, Mizuguchi M, Hayakawa S, Ushijima H
Organizer
第46回日本小児感染症学会学術集会
Place of Presentation
京王プラザホテル(東京都新宿区)
Year and Date
2014-10-18 – 2014-10-19
Related Report
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[Presentation] Recent trend of diarrheal viruses in Japan2014
Author(s)
Ushijima H, Takanashi S, Thongprachum A, Khamrin P, Okitsu S, Mizuguchi M, Hayakawa S.
Organizer
The 10th China-Japan International Conference of Virology
Place of Presentation
Xinmin Hotel (中国長春市)
Year and Date
2014-08-26 – 2014-08-28
Related Report
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[Presentation] Detection and genetic characterization of human cosavirus in a pediatric patient with diarrhea, Japan2014
Author(s)
Okitsu S, Khamrin P, Thongprachum A, Nishimura S, Takanashi S, Shimizu H, Hayakawa S, Ushijima H
Organizer
XVIth International Congress of Virology
Place of Presentation
Palais de congrès de Montréal, Montréal, Canada
Year and Date
2014-07-27 – 2014-08-01
Related Report
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[Presentation] Molecular and epidemiological trend of sapovirus and astrovirus infection in Japanese pediatric patients, 2009-2013
Author(s)
Thongprachum A, Takanashi S, Okitsu S, Kobayashi M, Nishimura S, Kikita H, Yamamoto A, Sugita K, Baba T, Mizuguchi M, Hayakawa S, Ushijima H
Organizer
第10回日本小児消化管感染症研究会
Place of Presentation
ヤクルトホール(東京都港区)
Related Report
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