The association among ferruginous body, uncoated fibers, asbestos and non-asbestos fibers in lung tissue
| Project/Area Number |
25460821
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hygiene and public health
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| Research Institution | Aichi Medical University |
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Principal Investigator |
Eiji Shibata 愛知医科大学, 医学部, 教授 (90206128)
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| Co-Investigator(Kenkyū-buntansha) |
SAKAKIBATA Yoko 愛知教育大学, 保健環境センター, 准教授 (90242891)
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| Research Collaborator |
SUZUKI Takayoshi
HISANAGA Naomi
SAKAI Kiyoshi
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 石綿 / 含鉄小体 / 石綿小体 / 位相差顕微鏡 / 肺内石綿濃度 / 剖検肺 / 角閃石系石綿 / ばく露指標 / 石綿関連疾患 / 角閃石 / クリソタイル / 鉄タンパク / 中皮腫 |
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| Outline of Final Research Achievements |
To demonstrate the correlations between the concentrations of ferruginous body as well as uncoated fiber both of which can be observed with phase-contrast microscope and the concentration of various inorganic fibers including asbestos which requires the observation with TEM or SEM, we measured those indices among Japanese and Korean cases. Though the concentration of ferruginous body in lung tissue is an important index of asbestos exposure, uncoated fibers observed with phase-contrast microscope might be another index especially in such cases with relatively low exposure due to their history of living in a general environment. However, to establish the reliability of uncoated fibers as an index of asbestos exposure, analysis with more cases and from various backgrounds must be carried out.
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Report
(4 results)
Research Products
(18 results)
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[Journal Article] The association among ferruginous body, uncoated fibers, asbestos and non-asbestos fibers in lung tissue in terms of length2016
Author(s)
Takayoshi SUZUKI, Yoko SAKAKIBARA, Naomi HISANAGA, Kiyoshi SAKAI, Il-Je YU, Hyun-Sul LIM, Hiroshige MIKAMO, Hiroshi SENO, Fumio KOBAYASHI and Eiji SHIBATA
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Journal Title
Industrial Health
Volume: 54
Issue: 4
Pages: 370-376
DOI
NAID
ISSN
0019-8366, 1880-8026
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Book] 胸膜全書2013
Author(s)
久永直見、酒井潔、柴田英治
Total Pages
399
Publisher
医薬ジャーナル社
Related Report
