A multiplex system using highly polymorphic INDEL markers in Japanese population and its forensic application
| Project/Area Number |
25460866
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Gifu University |
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Principal Investigator |
Nagai Atsushi 岐阜大学, 大学院医学系研究科, 准教授 (00207961)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | INDEL多型 / 個人識別 / 日本人集団 / 日本人 |
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| Outline of Final Research Achievements |
Using commercial INDEL polymorphism detection kit, I investigated the polymorphisms in the Japanese population for 30 INDEL markers included in the kit and compared the result with the data of other racial groups statistically, and I clarified the combined power of discrimination value of this kit in the Japanese population was lower than that in the Caucasian populations. Then, I selected 12 INDEL markers on autosome, which were highly polymorphic in the Japanese population and examined the multiplex INDEL polymorphism detection method using these markers. In addition, about INDEL-STR which I found in the process that selected the INDEL markers, I clarified the repeat number of the variable repeat block of STR are strongly associated with the INDEL polymorphism in the flanking region of STR.
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Report
(5 results)
Research Products
(2 results)
