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A multiplex system using highly polymorphic INDEL markers in Japanese population and its forensic application

Research Project

Project/Area Number 25460866
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Legal medicine
Research InstitutionGifu University

Principal Investigator

Nagai Atsushi  岐阜大学, 大学院医学系研究科, 准教授 (00207961)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
KeywordsINDEL多型 / 個人識別 / 日本人集団 / 日本人
Outline of Final Research Achievements

Using commercial INDEL polymorphism detection kit, I investigated the polymorphisms in the Japanese population for 30 INDEL markers included in the kit and compared the result with the data of other racial groups statistically, and I clarified the combined power of discrimination value of this kit in the Japanese population was lower than that in the Caucasian populations. Then, I selected 12 INDEL markers on autosome, which were highly polymorphic in the Japanese population and examined the multiplex INDEL polymorphism detection method using these markers. In addition, about INDEL-STR which I found in the process that selected the INDEL markers, I clarified the repeat number of the variable repeat block of STR are strongly associated with the INDEL polymorphism in the flanking region of STR.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2013

All Journal Article (1 results) Presentation (1 results)

  • [Journal Article] INDEL polymorphisms at the DXS10146 flanking region in four racial populations2013

    • Author(s)
      Atsushi. Nagai, Masaaki Hara, Tomomi Ishihara, Akiyoshi Tamura, Akira Kido, Yasuo Bunai
    • Journal Title

      Forensic Science International: Genetics Supplement Series

      Volume: 4 Issue: 1 Pages: e318-e319

    • DOI

      10.1016/j.fsigss.2013.10.162

    • Related Report
      2013 Research-status Report
  • [Presentation] INDEL Polymorphisms at the DXS10146 Flanking Region in Four Racial Populations2013

    • Author(s)
      A. Nagai, M. Hara, A. Tamura, A. Kido, Y. Bunai
    • Organizer
      The 25th World Congress of the International Society for Forensic Genetics
    • Place of Presentation
      Melbourne, Australia
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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