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Self Evaluation of Patients with Psychosomatic disorders - Elucidation of the Neural Basis and Efficacy of Cognitive Behavior Therapy

Research Project

Project/Area Number 25460884
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General internal medicine(including psychosomatic medicine)
Research InstitutionTohoku University

Principal Investigator

Sato Yasuhiro  東北大学, 大学病院, 助教 (20375033)

Co-Investigator(Kenkyū-buntansha) 田村 太作  東北大学, 大学病院, 助教 (60375029)
Project Period (FY) 2013-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords心身医学 / 神経科学 / 摂食障害 / 機能性消化管障害 / 心療内科学 / 脳画像 / 過敏性腸症候群 / 心身症 / 認知行動療法 / 自己評価 / 神経性やせ症 / 脳機能画像 / 神経性食思不振症
Outline of Final Research Achievements

Patients with psychosomatic disorders such as eating disorders and functional gastrointestinal disorders show poor self evaluation. Low self evaluation is relevant to onset and maintenace of the disorders. Social dysfunction by symptoms leads further impairment of self evaluation and these make a vicious circle. We conducted psychological evaluation of patients with eating disorders and acquired anatomical brain image, diffusion tensor image, and resting state functional magnetic resonance brain image. Patients of eating disorder showed poor Rosenberg's self-esteem scale score and showed thinner cortical surface in Precuneus and other regions than healthy controls. Resting state fMRI revealed that impaired functional connectivity between medial prefrontal cortex and temporal cortex which construct self-evaluation network.

Report

(5 results)
  • 2017 Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014 2013

All Journal Article (4 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (4 results) (of which Invited: 1 results)

  • [Journal Article] Gastrointestinal symptoms and disorders in patients with eating disorders.2015

    • Author(s)
      Yasuhiro Sato and Shin Fukudo
    • Journal Title

      Clin J Gastroenterol.

      Volume: 8 Issue: 5 Pages: 255-263

    • DOI

      10.1007/s12328-015-0611-x

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 脳の科学から見た摂食障害2015

    • Author(s)
      佐藤 康弘 福土 審
    • Journal Title

      精神科臨床サービス

      Volume: 15 Pages: 293-299

    • Related Report
      2015 Research-status Report
  • [Journal Article] 摂食障害における中枢神経系の変化(脳機能画像研究)2015

    • Author(s)
      佐藤 康弘 福土 審
    • Journal Title

      臨床栄養

      Volume: 127 Pages: 891-894

    • Related Report
      2015 Research-status Report
  • [Journal Article] 摂食障害と脳機能画像2013

    • Author(s)
      佐藤康弘 福土審
    • Journal Title

      臨床精神医学

      Volume: 42 Pages: 599-605

    • Related Report
      2013 Research-status Report
  • [Presentation] 摂食障害患者の脳機能と構造に関する多施設共同研究2016

    • Author(s)
      佐藤康弘
    • Organizer
      第4回心身医学のニューロサイエンス研究会
    • Place of Presentation
      大阪大学中之島センター、大阪
    • Year and Date
      2016-09-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] ストレス関連疾患としての摂食障害:脳画像研究からのアプローチ2016

    • Author(s)
      佐藤 康弘 福土審
    • Organizer
      第57回日本心身医学学会総会並びに学術大会
    • Place of Presentation
      仙台国際センター、仙台
    • Year and Date
      2016-06-05
    • Related Report
      2016 Annual Research Report
  • [Presentation] 神経性やせ症患者の認知柔軟性と意思決定2015

    • Author(s)
      佐藤 康弘 福土 審
    • Organizer
      第19回日本摂食障害学会
    • Place of Presentation
      パピヨン24(福岡市)
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 脳機能画像でみる摂食障害患者の認知機能2014

    • Author(s)
      佐藤 康弘  福土 審
    • Organizer
      第18回日本摂食障害学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-09-14
    • Related Report
      2014 Research-status Report
    • Invited

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Published: 2014-07-25   Modified: 2019-07-29  

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