Identification of molecules relating ICC disorder in murine diabetic gastroparesis
| Project/Area Number |
25460947
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HORIGUCHI SATOMI 福井大学, 医学部, 学術研究員 (00595283)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 糖尿病性胃不全麻痺 / カハール介在細胞 / 発現解析 / マウス / 糖尿病 / 消化管運動 |
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| Outline of Final Research Achievements |
Resent studies have suggested that disorders of the regulatory cells of the gastrointestinal motility, interstitial cells of Cajal (ICC), cause diabetic gastroparesis. In this study we compared the gene expression of ICC in diabetic db/db mice with those of wild type mice. By using DNA microarray we found some candidate genes related to the transformation and signal transduction.
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Report
(4 results)
Research Products
(13 results)
