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Objective Evaluation for Functional Bowel Disorder Using Video Capsule Endoscopy

Research Project

Project/Area Number 25461032
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Gastroenterology
Research InstitutionNagoya University

Principal Investigator

Nakamura Masanao  名古屋大学, 医学部附属病院, 助教 (60467321)

Co-Investigator(Kenkyū-buntansha) 大宮 直木  藤田保健衛生大学, 医学部, 教授 (00335035)
後藤 秀実  名古屋大学, 医学系研究科, 教授 (10215501)
山村 健史  名古屋大学, 医学部附属病院, 病院助教 (10709091)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywordsカプセル内視鏡 / 過敏性腸症候群 / 客観的評価 / 消化管運動機能 / 消化管機能 / 小腸
Outline of Final Research Achievements

We previously found the irregularity of the images of intestinal lumen on small bowel capsule endoscopy (CE) with irritable bowel syndrome (IBS) patients, comparing with those with healthy subjects. The aim of this study was to evaluate the detailed characteristics of the findings of intestinal lumens shown by CE images and to try to diagnose IBS objectively. The factor, abdominal pain, affected the passage of CE in the gastrointestinal tract. We considered that CE was useful for evaluating IBS with active phase. On the other hand, colon capsule endoscopy was not affected by abdominal symptoms. Therefore, our results suggested that the image analysis of small bowel CE images in active IBS may be important for diagnosing IBS.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (6 results)

All 2017 2016 2015 2014

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 2 results,  Acknowledgement Compliant: 3 results) Presentation (2 results)

  • [Journal Article] Prospective study of factors important to achieve observation of the entire colon on colon capsule endoscopy.2017

    • Author(s)
      Sato J, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Miyahara R, Kawashima H, Goto H, Hirooka Y.
    • Journal Title

      Therap Adv Gastroenterol.

      Volume: 10 Issue: 1 Pages: 20-31

    • DOI

      10.1177/1756283x16673556

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of mRNA and protein expression of nutritional biomarkers in the gastrointestinal mucosa of patients with small intestinal disorders2016

    • Author(s)
      Masanao Nakamura, Yoshiki Hirooka, Osamu Watanabe, Takeshi Yamamura, Kohei Funasaka, Eizaburo Ohno, Ryoji Miyahara, Hiroki Kawashima, Yoshie Shimoyama, Hidemi Goto
    • Journal Title

      Internal Medicine

      Volume: in press

    • NAID

      130005169386

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A Retrospective Evaluation of the Utility of Capsule Endoscopy and Double-Balloon Endoscopy in Crohn's Disease2016

    • Author(s)
      Masanao Nakamura, Yoshiki Hirooka, Osamu Watanabe, Takeshi Yamamura, Kohei Funasaka, Eizaburo Ohno, Hiroki Kawashima, Ryoji Miyahara, Hidemi Goto
    • Journal Title

      Gastroenterology Research and Practice

      Volume: in press Pages: 1-7

    • DOI

      10.1155/2016/1085027

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The Clinical Usefulness of the Novel Tag-Less Agile Patency Capsule Prior to Capsule Endoscopy for the Patients with Suspected Small Bowel Stenosis.2015

    • Author(s)
      Nakamura M, Hirooka Y, Watanabe O, Yamamura T, Furukawa K, Funasaka K, Ohno E, Miyahara R, Kawashima , Ando T, Ohmiya N, Goto H.
    • Journal Title

      Digestive Endoscopy

      Volume: 27 Issue: 1 Pages: 61-66

    • DOI

      10.1111/den.12306

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 大腸カプセル内視鏡における全大腸観察を達成するために重要な臨床因子の検討2016

    • Author(s)
      佐藤淳一、廣岡芳樹、渡辺修、中村正直、山村健史、後藤秀実
    • Organizer
      第12回日本消化管学会総会学術集会
    • Place of Presentation
      東京都新宿区 京王プラザホテル
    • Year and Date
      2016-02-26
    • Related Report
      2015 Research-status Report
  • [Presentation] The Clinical Experiences of Novel Tag-Less Agile Patency Capsule for 100 Cases With Suspected Small Bowel Stenosis2014

    • Author(s)
      Nakamura M, Hirooka Y, Yamamura T, Yamada K, Nagura A, Yoshimura T, Nakano A, Oshima H, Furukawa K, Funasaka K, Ohno E, Miyahara R, Kawashima H, Itoh A, Watanabe O, Ando T, Ohmiya N, Goto H
    • Organizer
      Digestive Disease Week in America
    • Place of Presentation
      Chicago,U.S.A
    • Year and Date
      2014-05-05
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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