| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
1) Consecutive 100 patients with paroxysmal atrial fibrillation (AF) who underwent AF ablation were enrolled. Blood samples were simultaneously collected from the left atrial (LA) and systemic circulation (SC). The prevalence of positive LA-D-dimer was greater than that of SC-D-dimer (P<0.01). LA volume index was independently correlated with positive LA-D-dimer (P=0.011). The prevalence of positive LA-D-dimer was significantly lower in patients taking continuous warfarin, than in those on discontinuous warfarin (P=0.025).
2) In 20 patients with AF who underwent 123I-MIBG imaging on the day before and several days after the ganglionated plexi ablation, there was no difference in any MIBG parameters between the values before and after the ablation
3) A total of 50 consecutive patients with paroxysmal AF were randomized to receive either landiolol or a placebo. The prevalence of immediate AF recurrence was significantly lower in the landiolol group than in the placebo group (P=0.015).
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