Development of the pressure variable controlled tidal expiratory flow monitoring device

• Project/Area Number: 25461146
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Respiratory organ internal medicine
• Research Institution: Tohoku University
• Principal Investigator: Ogawa hiromasa 東北大学, 環境・安全推進センター, 准教授 (90361162)
• Co-Investigator(Kenkyū-buntansha): KUROSAWA Hajime 東北大学, 環境・安全推進センター, 教授 (60333788) ; IROKAWA Toshiya 東北大学, 環境・安全推進センター, 准教授 (70375179)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
• Keywords: 呼吸機能 / 換気障害診断 / NEP / スパイロメトリー / 換気障害 / COPDスクリーニング / 呼吸機能検査

Outline of Final Research Achievements

This aim is to develop a new cooperation-free simple measuring device as a substitute for spirometer.We have developed a new device to monitor the change in tidal expiratory flow by applying variable negative pressure at the mouth during tidal expiration.The tidal expiratory flow increased by increasing the negative pressure during tidal expiration. The reduction in increment of the tidal expiratory flow occurred in obstructive ventilatory impairment. The change in increment of the tidal expiratory flow by variable negative expiratory pressure was shown to be useful for detecting ventilatory impairments. This result suggests that this new cooperation-free simple measuring developed device, is a substitute for spirometer.

Research Products

• [Presentation] 新しい呼気陰圧負荷機器の開発：換気障害指標の確立 (2016)
  • Author(s): 小川 浩正
  • Organizer: 第56回日本呼吸器学会学術講演会
  • Place of Presentation: 京都市（国立京都国際会館）
  • Year and Date: 2016-04-08
• [Presentation] 新しい呼気陰圧負荷機器の開発 (2015)
  • Author(s): 小川浩正
  • Organizer: 第55回日本呼吸器学会学術講演会
  • Place of Presentation: 東京国際フォーラム（東京都）
  • Year and Date: 2015-04-17 – 2015-04-19
• [Remarks] 知と医療機器創生宮城県エリア 生体計測機器 可変圧負荷安静呼吸流速測定機器の開発
  • URL: http://sendai-cyber.icr-eq.co.jp/project/development/files/development_05_03.pdf
• [Remarks] 知と医療機器創生宮城県エリア プロジェクト 医療機器研究開発 生態計測機器
  • URL: http://sendai-cyber.icr-eq.co.jp/project/development/development_05.html