| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
We investigated whether microparticle（MP）can be one of the clinical markers for inflammatory lung diseases (ILD). MP was detectable in bronchoalveolar lavage fluid by FACS and its concentration was correlated with number of white blood cells, but not with serum markers such as CRP, LDH and KL-6. The patients with ILD who eventually died did not show high MP. When a cell line (A549) was induced to apoptosis or activated state, MP concentration in the supernatant was increased. These data suggested that MP may have certain significance in ILD, but still not be available as a clinical marker.
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