Memory T cell differentiation in GVHD and GVL

• Project/Area Number: 25461453
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hematology
• Research Institution: Kyushu University
• Principal Investigator: Kato Koji 九州大学, 大学病院, 助教 (20571764)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 造血幹細胞移植学 / メモリーT細胞 / GVHD

Outline of Final Research Achievements

T memory stem cell (TMSC) has reportedly played an important role in development of severe GVHD in mice. However, there is little information about the relation between TMSC and GVHD. We showed that TMSC was enriched after administration of post-cyclophosphamide　in haplo-matched allogeneic stem cell transplantation. These TMSC did not lead to development of GVHD. Furthermore, the incidence of infectious complications was very low through the rapid immunological reconstitution. These data suggested that TMSC was a key subset of the separation between GVHD and GVL.

Research Products

• [Journal Article] 急性骨髄性白血病第1寛解期における同種造血幹細胞移植 (2016)
  • Author(s): 加藤 光次
  • Journal Title: 血液内科 Volume: 72 Pages: 172-178
• [Journal Article] Cord Blood Transplantation Following Reduced-intensity Conditioning for Adult-onset Inherited Hemophagocytic Lymphohistiocytosis. (2016)
  • Author(s): Kuriyama T, Kato K, Sakamoto K, Hayashi M, Takashima S, Mori Y, Takenaka K, Iwasaki H, Teshima T, Harada N, Nagafuji K, Miyamoto T, Akashi K
  • Journal Title: Intern Med Volume: 55 Pages: 667-671
  • NAID: 130005138087
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] BiTE抗体の臨床開発の現状 (2016)
  • Author(s): 加藤 光次
  • Journal Title: がん分子標的治療 Volume: 14 Pages: 98-103
• [Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice. (2015)
  • Author(s): Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.
  • Journal Title: Blood Volume: 90 Pages: 3014-3023
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Effects of conditioning intensity in allogeneic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia. (2015)
  • Author(s): Takashima S, Miyamoto T, Kamimura T, Yoshimoto G, Yoshida S, Henzan H, Takase K, Kato K, Ito Y, Ohno Y, Nagafuji K, Eto T, Teshima T, Akashi K.
  • Journal Title: Int J Hematol Volume: 102 Pages: 689-696
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Successful treatment of adult Langerhans cell histiocytosis with intensified chemotherapy. (2015)
  • Author(s): Minami M, Shima T, Kato K, Yamamoto H, Tsuchihashi K, Oku S, Shimokawa T, Tochigi T, Yoshimoto G, Kamezaki K, Takenaka K, Iwasaki H, Oda Y, Miyamoto T, Akashi K.
  • Journal Title: Int J Hematol Volume: 102 Pages: 244-248
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Recent Advances in Therapeutic Approaches for Adult T-cell Leukemia/Lymphoma. (2015)
  • Author(s): Kato K, Akashi K.
  • Journal Title: Viruses Volume: 7 Pages: 102-106
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The role of hematopoietic stem cell transplantation for acute myeloid leukemia (2015)
  • Author(s): 加藤 光次
  • Journal Title: Rinsho Ketsueki Volume: 56 Issue: 10 Pages: 1950-1959
  • DOI: 10.11406/rinketsu.56.1950
  • NAID: 130005103299
  • ISSN: 0485-1439, 1882-0824
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Characteristics of patients with development of large granular lymphocyte expansion among dasatinib-treated patients with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic stem cell transplantation. (2015)
  • Author(s): Ito Y, Miyamoto T, Kamimura T, Aoki K, Henzan H, Aoki T, Shiratsuchi M, Kato K, Nagafuji K, Ogawa R, Eto T, Iwasaki H, Akashi K.
  • Journal Title: Clin Lymphoma Myeloma Leuk. Volume: 15 Issue: 3 Pages: 47-54
  • DOI: 10.1016/j.clml.2014.09.006
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The role of hematopoietic stem cell transplantation for relapsed and refractory Hodgkin lymphoma. (2015)
  • Author(s): Kako S, Izutsu K, Kato K, Kim SW, Mori T, Fukuda T, Kobayashi N, Taji H, Hashimoto H, Kondo T, Sakamaki H, Morishima Y, Kato K, Suzuki R, Suzumiya J; on behalf of the Adult Lymphoma Working Group of the Japanese Society for Hematopoietic Cell Transplantation.
  • Journal Title: Am J Hematol. Volume: 90 Issue: 2 Pages: 132-138
  • DOI: 10.1002/ajh.23897
  • Peer Reviewed / Open Access
• [Journal Article] High-dose chemotherapy with autologous stem cell transplantation for elderly patients with relapsed/refractory diffuse large B-cell lymphoma: a nationwide retrospective study. Biol Blood Marrow Transplant. (2014)
  • Author(s): Chihara D, Izutsu K, Kondo E, Sakai R, Mizuta S, Yokoyama K, Kaneko H, Kato K, Hasegawa Y, Chou T, Sugahara H, Henzan H, Sakamaki H, Suzuki R, Suzumiya J.
  • Journal Title: Biol Blood Marrow Transplant. Volume: 20 Issue: 5 Pages: 684-689
  • DOI: 10.1016/j.bbmt.2014.01.025
  • Peer Reviewed / Open Access
• [Journal Article] The ordered acquisition of Class II and Class I mutations directs formation of human t(8;21) acute myelogenous leukemia stem cell. (2014)
  • Author(s): Shima T, Miyamoto T, Kikushige Y, Yuda J, Tochigi T, Yoshimoto G, Kato K, Takenaka K, Iwasaki H, Mizuno S, Goto N, Akashi K.
  • Journal Title: Exp. Hematol. Volume: 42 Issue: 11 Pages: 955-65
  • DOI: 10.1016/j.exphem.2014.07.267
  • Peer Reviewed / Open Access
• [Journal Article] Combination of bortezomib, thalidomide, and dexamethasone (VTD) as a consolidation therapy after autologous stem cell transplantation for symptomatic multiple myeloma in Japanese patients. (2014)
  • Author(s): Takashima S, Miyamoto T, Kadowaki M, Ito Y, Aoki T, Takase K, Shima T, Yoshimoto G, Kato K, Muta T, Shiratsuchi M, Takenaka K, Iwasaki H, Teshima T, Kamimura T, Akashi K.
  • Journal Title: Int J Hematol Volume: 100 Issue: 2 Pages: 159-164
  • DOI: 10.1007/s12185-014-1611-1
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Treatment of Patients with Adult T Cell Leukemia/Lymphoma with Cord Blood Transplantation: A Japanese Nationwide Retrospective Survey. (2014)
  • Author(s): Kato K, Choi I, Wake A, Uike N, Taniguchi S, Moriuchi Y, Miyazaki Y, Nakamae H, Oku E, Murata M, Eto T, Akashi K, Sakamaki H, Kato K, Suzuki R, Yamanaka T, Utsunomiya A.
  • Journal Title: Biol Blood Marrow Transplant. Volume: 20 Issue: 12 Pages: 1968-1974
  • DOI: 10.1016/j.bbmt.2014.08.012
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Long-term remission after high-dose chemotherapy followed by auto-SCT as consolidation for intravascular large B-cell lymphoma. (2014)
  • Author(s): Kato K, Ohno Y, Kamimura T, Kusumoto H, Tochigi T, Jinnouchi F, Kohno K, Kuriyama T, Henzan H, Takase K, Kawano I, Kadowaki M, Nawata R, Muta T, Eto T, Iawasaki H, Ohshima K, Miyamoto T, Akashi K.
  • Journal Title: Bone Marrow Transplant. Volume: 49 Issue: 12 Pages: 1543-1544
  • DOI: 10.1038/bmt.2014.189
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Evaluation of the feasibility and efficacy of autologous stem cell transplantation in elderly patients with multiple myeloma. (2013)
  • Author(s): Muta T, Miyamoto T, Fujisaki T, Ohno Y, Kamimura T, Kato K, Takenaka K, Iwasaki H, Eto T, Takamatsu Y, Teshima T, Akashi K; Fukuoka Blood and Marrow Transplant Group (FBMTG).
  • Journal Title: Intern Medcine Volume: 52 Pages: 63-70
  • NAID: 130003365558
  • Peer Reviewed
• [Journal Article] Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia/lymphoma. (2013)
  • Author(s): Kato K, Miyamoto T, Numata A, Nakaike T, Oka H, Yurino A, Kuriyama T, Mori Y, Yamasaki S, Muta T, Takenaka K, Iwasaki H, Teshima T, Akashi K.
  • Journal Title: Int J Hematol. Volume: 97 Issue: 3 Pages: 430-2
  • DOI: 10.1007/s12185-013-1278-z
  • NAID: 10031162910
  • Peer Reviewed
• [Journal Article] Antiemetic effectiveness and safety of aprepitant in patients with hematologic malignancy receiving multiday chemotherapy. (2013)
  • Author(s): Uchida M
  • Journal Title: Am J Health Syst Pharm Volume: 70 Issue: 4 Pages: 343-349
  • DOI: 10.2146/ajhp120363
  • Peer Reviewed
• [Journal Article] Effect of bortezomib-based induction therapy on the peripheral blood stem cell harvest in multiple myeloma. (2013)
  • Author(s): Muta T, Miyamoto T, Fujisaki T, Ohno Y, Kamimura T, Henzan T, Kato K, Takenaka K, Iwasaki H, Eto T, Takamatsu Y, Teshima T, Akashi K; Fukuoka Blood and Marrow Transplant Group (FBMTG).
  • Journal Title: Rinsho Ketsueki. Volume: 54 Pages: 109-116
  • NAID: 10031147827
  • Peer Reviewed
• [Journal Article] Decrease in venous irritation by adjusting the concentration of injected bendamustine. (2013)
  • Author(s): Watanabe H, Ikesue H, Tsujikawa T, Nagata K, Uchida M, Suetsugu K, Egashira N, Muta T, Kato K, Takenaka K, Ohga S, Matsushima T, Shiratsuchi M, Miyamoto T, Teshima T, Akashi K, Oishi R.
  • Journal Title: Biol Pharm Bull Volume: 36 Pages: 574-578
  • NAID: 130003361397
  • Peer Reviewed
• [Journal Article] Standardization of image quality across multiple centers by optimization of acquisition and reconstruction parameters with interim FDG-PET/CT for evaluating diffuse large B cell lymphoma. (2013)
  • Author(s): Daisaki H, Tateishi U, Terauchi T, Tatsumi M, Suzuki K, Shimada N, Nishida H, Numata A, Kato K, Akashi K, Harada M.
  • Journal Title: Ann Nucl Med. Volume: 27 Issue: 3 Pages: 225-232
  • DOI: 10.1007/s12149-012-0676-2
  • NAID: 10031168088
  • Peer Reviewed
• [Journal Article] Delta-Like Ligand 4 Identifies a Previously Uncharacterized Population of Inflammatory Dendritic Cells That Plays Important Roles in Eliciting Allogeneic T Cell Responses in Mice. (2013)
  • Author(s): Mochizuki K, Xie F, He S, Tong Q, Liu Y, Mochizuki I, Guo Y, Kato K, Yagita H, Mineishi S, Zhang Y.
  • Journal Title: J Immunol. Volume: 190 Issue: 7 Pages: 3772-3782
  • DOI: 10.4049/jimmunol.1202820
  • Peer Reviewed
• [Journal Article] Potential contribution of a novel Taxepitope-specific CD4+ T cells tograftversus-Tax effects in adult T-cell leukemia patients after allogeneichematopoietic stem celltransplantation. (2013)
  • Author(s): Tamai Y., Hasegawa A., Takamori A., et al.
  • Journal Title: Journal of Immunology Volume: in press Issue: 8 Pages: 4382-4392
  • DOI: 10.4049/jimmunol.1202971
  • Peer Reviewed
• [Journal Article] Effectiveness and safety of antiemetic aprepitant in Japanese patients receiving high-dose chemotherapy prior to autologous hematopoietic stem cell transplantation. (2013)
  • Author(s): Uchida M, Ikesue H, Miyamoto T, Kato K, Suetsugu K, Ichinose K, Hiraiwa H, Sakurai A, Takenaka K, Muta T, Iwasaki H, Teshima T, Shiratsuchi M, Egashira N, Akashi K, Oishi R.
  • Journal Title: Biol Pharm Bull. Volume: 36 Pages: 819-824
  • NAID: 130003361413
  • Peer Reviewed
• [Journal Article] Efficacy and Safety of Aprepitant in Allogeneic Hematopoietic Stem Cell Transplantation. Pharmacotherapy. (2013)
  • Author(s): Uchida M, Kato K, Ikesue H, Ichinose K, Hiraiwa H, Sakurai A, Muta T, Takenaka K, Iwasaki H, Miyamoto T, Teshima T, Shiratsuchi M, Suetsugu K, Nagata K, Egashira N, Akashi K, Oishi R.
  • Journal Title: Pharmacotherapy Volume: 33 Issue: 9 Pages: 893-901
  • DOI: 10.1002/phar.1294
  • Peer Reviewed
• [Journal Article] Evaluating the association between histological manifestations of cord colitis syndrome with GVHD. (2013)
  • Author(s): Shimoji S, Kato K, Eriguchi Y, Takenaka K, Iwasaki H, Miyamoto T, Oda Y, Akashi K, Teshima T
  • Journal Title: Bone Marrow Transplant Volume: 48 Issue: 9 Pages: 1249-1252
  • DOI: 10.1038/bmt.2013.44
  • Peer Reviewed
• [Journal Article] Combination of high-dose melphalan and bortezomib as conditioning regimen for autologous peripheral blood stem cell transplantation in multiple myeloma. (2013)
  • Author(s): Miyamoto T, Yoshimoto G, Kamimura T, Muta T, Takashima S, Ito Y, Shiratsuchi M, Choi I, Kato K, Takenaka K, Iwasaki H, Takamatsu Y, Teshima T, Akashi K.
  • Journal Title: Int J Hematol Volume: 98 Issue: 3 Pages: 337-345
  • DOI: 10.1007/s12185-013-1402-0
  • Peer Reviewed
• [Journal Article] Clinical outcomes of allogeneic stem cell transplantation for relapsed or refractory follicular lymphoma: a retrospective analysis by the Fukuoka Blood and Marrow Transplantation Group. (2013)
  • Author(s): 107 Ito Y, Miyamoto T, Kamimura T, Takase K, Henzan H, Sugio Y, Kato K, Ohno Y, Eto T, Teshima T, Akashi K
  • Journal Title: Int J Hematol Volume: 98 Issue: 4 Pages: 463-471
  • DOI: 10.1007/s12185-013-1430-9
  • Peer Reviewed
• [Journal Article] Impact of graft-versus-host disease on allogeneic hematopoietic cell transplantation for adult T cell leukemia-lymphoma focusing on preconditioning regimens: nationwide retrospective study. (2013)
  • Author(s): Ishida T, Hishizawa M, Kato K, Tanosaki R, Fukuda T, Takatsuka Y, Eto T, Miyazaki Y, Hidaka M, Uike N, Miyamoto T, Tsudo M, Sakamaki H, Morishima Y, Suzuki R, Utsunomiya A.
  • Journal Title: Biol Blood Marrow Transplant. Volume: 19(12) Issue: 12 Pages: 1731-1739
  • DOI: 10.1016/j.bbmt.2013.09.014
  • Peer Reviewed
• [Journal Article] Superiority of tandem autologous stem cell transplantation using high dose melphalan for patients with multiple myeloma. (2013)
  • Author(s): Muta T, Kamimura T, Miyamoto T, Ohno Y, Henzan T, Kato K, Takenaka K, Iwasaki H, Fujisaki T, Eto T, Akashi K.
  • Journal Title: International Journal of Myeloma Volume: 3
  • Peer Reviewed
• [Journal Article] Reduced-intensity conditioning followed by cord blood transplantation in a patient with refractory folliculotropic mycosis fungoides. (2013)
  • Author(s): Nakaike T, Kato K, Oku S, Hayashi M, Kikushige Y, Kuroiwa M, Takenaka K, Iwasaki H, Miyamoto T, Teshima T, Ohshima K, Akashi K.
  • Journal Title: Int J Hematol. Volume: 98 Issue: 4 Pages: 491-495
  • DOI: 10.1007/s12185-013-1410-0
  • Peer Reviewed
• [Journal Article] Successful treatment with anti-CC chemokine receptor 4 MoAb of relapsed adult T-cell leukemia/lymphoma after umbilical cord blood transplantation. (2013)
  • Author(s): Ito Y, Miyamoto T, Chong Y, Aoki T, Kato K, Akashi K, Kamimura T.
  • Journal Title: Bone Marrow Transplant Volume: 48 Issue: 7 Pages: 998-999
  • DOI: 10.1038/bmt.2012.268
  • Peer Reviewed
• [Journal Article] Quantification of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic stem cell transplantation. (2013)
  • Author(s): Shima T
  • Journal Title: Blood Volume: 121 Issue: 5 Pages: 840-848
  • DOI: 10.1182/blood-2012-02-409607
  • Peer Reviewed
• [Presentation] ホジキンリンパ腫と末梢性T細胞性リンパ腫: 希少リンパ腫治療の新展開 (2016)
  • Author(s): 加藤 光次
  • Organizer: 第6回日本血液学会九州地方会
  • Place of Presentation: 福岡
  • Year and Date: 2016-03-19
  • Invited
• [Presentation] Brentuximab vedotin 時代の悪性リンパ腫治療 (2016)
  • Author(s): 加藤 光次
  • Organizer: 第38回造血細胞移植学会
  • Place of Presentation: 名古屋
  • Year and Date: 2016-03-04
  • Invited
• [Presentation] FDG PET/CT の定量的評価による治療抵抗性悪性リンパ腫に対する同種造血幹細胞移植の 有効性の予測 (2016)
  • Author(s): 杉尾 健志、加藤 光次、馬場 眞吾、宮脇 恒太、森 康雄、吉本 五一、亀崎健次郎、竹中 克斗、岩崎 浩己、宮本 敏浩、赤司 浩一
  • Organizer: 第38回造血細胞移植学会
  • Place of Presentation: 名古屋
  • Year and Date: 2016-03-04
• [Presentation] Immunohistochemical Expression Pattern of Programmed Cell Death Ligand 1 Might be Both Good and Bad Prognostic Factor in Adult T-Cell Leukemia/ Lymphoma (2015)
  • Author(s): Miyoshi Hiroaki, Junichi Kiyasu, Takeharu Kato, Noriaki Yoshida, Daisuke Kurita, Sasaki Yuya, Koji Kato, Yoshitaka Imaizumi, Masao Seto, Koichi Akashi, Koichi Ohshima
  • Organizer: 第57回アメリカ血液学会年次集会
  • Place of Presentation: 米国オーランド
  • Year and Date: 2015-12-04
  • Int'l Joint Research
• [Presentation] Comparative Analysis of Tyrosine Kinase Inhibitors-Related Pulmonary Hypertension in the Patients Treated By Imatinib, Dasatinib and Nilotinib (2015)
  • Author(s): Mariko Minami, Toshihiro Miyamoto, Takeshi Arita, Tomohiko Kamimura, Junichiro Yuda, Yoshikane Kikushige, Yasuo Mori, Goichi Yoshimoto, Kenjiro Kamezaki, Koji Kato, Motoaki Shiratsuchi, Katsuto Takenaka, Hiromi Iwasaki, Satoshi Yamasaki, Tsuyoshi Muta, Kazuki Tanimoto, Ryosuke Ogawa, Tetsuya Eto, Koichi Akashi
  • Organizer: 第57回アメリカ血液学会年次集会
  • Place of Presentation: 米国オーランド
  • Year and Date: 2015-12-04
  • Int'l Joint Research
• [Presentation] Incidence and Differential Diagnosis of Human Herpes Virus-6 Associated Encephalitis/Myelitis in Allogeneic Stem Cell Transplantation That Mimics Calcineurin Inhibitor-Induced Pain Syndrome (2015)
  • Author(s): Goichi Yoshimoto, Toshihiro Miyamoto, Koji Kato, Yasuo Mori, Kenjiro Kamezaki, Katsuto Takenaka, Hiromi Iwasaki, Koichi Akashi
  • Organizer: 第57回アメリカ血液学会年次集会
  • Place of Presentation: 米国オーランド
  • Year and Date: 2015-12-04
  • Int'l Joint Research
• [Presentation] 杉尾 健志, 加藤 光次, 平安山 英穂, 青木 孝友, 伊藤 能清, 齋藤 統之, 吉田 周郎, 河野 一郎, 太田 貴徳, 門脇 賢典, 高瀬 謙, 宮脇 恒太, 山内 拓司, 島 隆弘, 高嶋 秀一郎, 森 康雄, 吉本 五一, 亀崎 健次郎, 竹中 克斗, 岩崎 浩己, 上村 智彦, 大野 裕樹, 衛藤 徹也, 宮本 敏浩, 赤司 浩一 (2015)
  • Author(s): Prior use of mogamulizumab to allo-HSCT induces severe acute GVHD
  • Organizer: 第77回日本血液学会学術集会
  • Place of Presentation: 金沢
  • Year and Date: 2015-10-17
• [Presentation] Clinical outcome of allo-HSCT for relapsed ATLL after chemotherapy: the JCHCT ATL-WG study (2015)
  • Author(s): 藤原 弘, 藤 重夫, 和氣 敦, 加藤 光次, 高塚 祥芝, 福田 隆浩, 田口 潤, 内田 直之 , 宮本 敏浩, 日高 道弘, 宮崎 泰彦, 友寄 毅昭, 長村 登紀子, 森島 泰雄, 一戸 辰夫, 熱田 由子, 宇都宮 與
  • Organizer: 第77回日本血液学会学術集会
  • Place of Presentation: 金沢
  • Year and Date: 2015-10-17
• [Presentation] 急性骨髄性白血病における移植の位置づけ (2015)
  • Author(s): 加藤 光次
  • Organizer: 第77回日本血液学会学術集会
  • Place of Presentation: 金沢
  • Year and Date: 2015-10-16
  • Invited
• [Presentation] Allogeneic stem cell transplantation for acute myeloid leukemia in primary induction failure (2015)
  • Author(s): 吉本 五一, 加藤 光次, 小田原 淳, 森 康雄, 亀崎 健次郎, 上村 智彦, 竹中 克斗, 岩崎 浩己, 大野 裕樹, 衛藤 徹也, 宮本 敏浩, 赤司 浩一
  • Organizer: 第77回日本血液学会学術集会
  • Place of Presentation: 金沢
  • Year and Date: 2015-10-16
• [Presentation] 同種造血幹細胞移植における移植後女性不妊の原因 (2015)
  • Author(s): 下地 園子, 加藤 光次, 橋本 大吾, 辻極 秀次, 宮本 敏浩, 竹中 克斗, 岩崎 浩己, 赤司 浩一, 豊嶋 崇徳
  • Organizer: 第112回日本内科学会総会
  • Place of Presentation: 京都
  • Year and Date: 2015-04-11
• [Presentation] Graft-Versus-Host Disease Targets Granulosa Cell of Ovarian Follicle and Causes Infertility after Allogeneic Hematopoietic Stem Cell Transplantation (2015)
  • Author(s): Shimoji S, Hashimoto D, Kato K, Tujigiwa H, Akashi K, Teshima T
  • Organizer: 2015 BMT Tandem Meetings
  • Place of Presentation: サンデイエゴ(USA)
  • Year and Date: 2015-02-11 – 2015-02-14
• [Presentation] Risk Stratification of Outcomes Among Patients with Adult T-Cell Leukemia/Lymphoma Receiving Allogeneic Hematopoietic Cell Transplantation: A Retrospective Analysis of the JSHCT ATL Working Group (2015)
  • Author(s): Yoshimitsu M, Tanosaki R, Kato K, Ishida T, Choi I, Fukuda T, Takatsuka Y, Eto T, Uchida N, Moriuchi Y, Nagamura-Inoue T, Mori S, Sakamaki H, Atsuta Y, Utsunomiya A
  • Organizer: 2015 BMT Tandem Meetings
  • Place of Presentation: サンデイエゴ(USA)
  • Year and Date: 2015-02-11 – 2015-02-14
• [Presentation] Second Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) for Relapse of Hematological Malignancies after First Allo-HSCT (2014)
  • Author(s): Kato K, Miyamoto T, Yonemoto K, Uchida N, Ogawa H, Fukuda T, Takahashi S, Ohashi K, Eto T, Nagamura-Inoue T, Sakamaki H, Morishima Y, Suzuki R, Atsuta Y, Akashi K
  • Organizer: 第56回アメリカ血液学会年次集会
  • Place of Presentation: サンフランシスコ(USA)
  • Year and Date: 2014-12-05 – 2014-12-09
• [Presentation] High-dose chemotherapy followed by auto-PBSCT for intravascular large B-cell lymphoma(IVLBCL) (2014)
  • Author(s): Kato K, Mori T, Kim S, Sawa M, Sakai T, Hashimoto H, Taguchi J, Tanaka J, Nagamura-Inoue T, morishima Y, Suzuki R, Suzumiya J.
  • Organizer: 第76回日本血液学会学術集会
  • Place of Presentation: 大阪
  • Year and Date: 2014-10-31 – 2014-11-02
• [Presentation] Graft-Versus-Host Disease targets ovary and causes infertilith after allo-HSCT (2014)
  • Author(s): Shimoji S, Kato K, Tujigawa H, Eriguchi Y, Uryu H, Takashima S, Hashimoto D, Miyamoto T, Uwasaki H, Akashi K, Teshima T.
  • Organizer: 第76回日本血液学会学術集会
  • Place of Presentation: 大阪
  • Year and Date: 2014-10-31 – 2014-11-02
• [Presentation] 悪性リンパ腫の治療の現況 (2014)
  • Author(s): 加藤光次
  • Organizer: 第12回日本臨床腫瘍学会学術集会
  • Place of Presentation: 福岡
  • Year and Date: 2014-07-18
  • Invited
• [Presentation] 成人T細胞性白血病/リンパ腫の治療の現在、そして未来 (2014)
  • Author(s): 加藤光次
  • Organizer: 第54回日本網内系学会総会
  • Place of Presentation: 山形
  • Year and Date: 2014-06-21
  • Invited
• [Presentation] High-dose chemotherapy with autologous stem cell transplantation for elderly patients with relapsed/refractory diffuse large B-cell lymphoma: A retrospective from the adult lymphma working group of the JSHCT (2013)
  • Author(s): Chihara D, Izutsu K, Kondo E, Sakai R, Mizuta S, Yokoyama K, Kaneko H, Kato K, Sakamaki H., Suzuki R, Suzumiya J
  • Organizer: 12th International conference on malignant lymphoma
  • Place of Presentation: Lugano, Switzerland
• [Presentation] Cord blood transplantation for adult T-cell leukemia/lymphoma (ATL): A retrospective analysis from the ATL working group of the JSHCT (2013)
  • Author(s): Koji Kato, Ilseung Cho, Atsushi Wake, Naokuni Uike, Shuichi Taniguchi, Yukiyoshi Moriuchi, Yasushi Miyazaki, Masayuki Hino, Koichi Akashi, Hisashi Sakamaki, Koji Kato, Ritsuro Suzuki, Takeharu Yamanaka, Atae Utsunomiya
  • Organizer: 12th International conference on malignant lymphoma
  • Place of Presentation: Lugano, Switzerland
• [Presentation] Successful treatment of allogeneic SCT in a patient with common variable immunodeficiency (2013)
  • Author(s): 下地 園子, 加藤 光次, 石塚 賢治, 栗山 拓郎, 西田 留梨子, 竹中 克斗, 岩崎 浩己, 宮本 敏浩, 豊嶋 崇徳, 赤司 浩一
  • Organizer: 第75回日本血液学会学術集会
  • Place of Presentation: 札幌
• [Presentation] 移植前肝炎ウイルスの有無がリンパ腫の移植成績に及ぼす影響－JSHCT成人悪性リンパ腫WGからの報告 (2013)
  • Author(s): 加藤 春美, 千原 大, 加藤 光次, 金 成元, 福田 隆浩, 森 毅彦, 谷口 修一, 澤 正史, 大野 裕樹, 坂巻 壽, 加藤 剛二, 森島 泰雄, 鈴木 律朗, 鈴宮 淳司
  • Organizer: 第75回日本血液学会学術集会
  • Place of Presentation: 札幌
• [Presentation] Leukemogenic function of TIM-3, a leukemia stem cell marker, in acute myelogenous leukemia (2013)
  • Author(s): 湯田 淳一朗, 菊繁 吉謙, 宮本 敏浩, 島 隆宏, 飯野 忠史, 加藤 光次, 牟田 毅, 竹中 克斗, 岩崎 浩己, 赤司 浩一
  • Organizer: 第75回日本血液学会学術集会
  • Place of Presentation: 札幌
• [Presentation] HHV-6-assosiated encephalitis and / or myelitis: Retrospective analysis of 374 cases (2013)
  • Author(s): 吉本 五一, 宮本 敏浩, 島 隆宏, 高嶋 秀一郎, 亀崎 健次郎, 加藤 光次, 牟田 毅, 竹中 克斗, 岩崎 浩己, 赤司 浩一
  • Organizer: 第75回日本血液学会学術集会
  • Place of Presentation: 札幌
• [Presentation] Graft-Versus-Host Disease Targets Ovary and Causes Infertility After Allogeneic Hematopoietic Stem Cell Transplantation (2013)
  • Author(s): Sonoko Shimoji, Koji Kato, Hidetsugu Tsujigiwa, Yoshihiro Eriguchi, Lifa Lee, Hidetaka Uryu, Shuichiro Takashima, Daigo Hashimoto, Koichi Akashi, Takanori Teshima
  • Organizer: 55th Annual Meeting and Exposition, American Society of Hematology
  • Place of Presentation: New Orleans, USA
• [Presentation] Mobilization of Human Immature Hematopoietic Progenitors after Combinatory Use of Bortezomib and Immunomodulatory Drugs
  • Author(s): Taro Tochigi, Takatoshi Aoki, Yoshikane Kikushige, Tomohiko Kamimura, Takuji Yamauchi, Koji Kato, Katsuto Takenaka, Toshihiro Miyamoto, Koichi Akashi
  • Organizer: 第57回アメリカ血液学会年次集会
  • Place of Presentation: 米国オーランド
  • Int'l Joint Research
• [Presentation] Prior Use of Mogamulizumab to Allogenic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-Versus-Host Disease
  • Author(s): Sugio T, Kato K, Aoki T, Ota T, Saito N, Yoshida S, Kawano I, Henzan H, Takase K, Muta T, Miyawaki K, Shima T, Takashima S, Yamauchi T, Mori Y, Yoshimoto G, Kamezaki K, Takenaka K, Kamimura T, Ohno Y, Eto T, Ogawa R, Iwasaki H, Miyamoto T, Akashi K
  • Organizer: 第57回アメリカ血液学会年次集会
  • Place of Presentation: 米国オーランド
  • Int'l Joint Research
• [Book] 血液専門医テキスト (2015)
  • Author(s): 加藤光次
  • Total Pages: 10
  • Publisher: 南江堂
• [Book] ファーマナビゲーターDIC編 (2014)
  • Author(s): 加藤光次、丸山征郎
  • Total Pages: 8
  • Publisher: メディカルレビュー社
• [Book] みんなに役立つGVHDの基礎と臨床 「新規薬剤がGVHDに及ぼす影響」 (2013)
  • Author(s): 加藤 光次
  • Total Pages: 8
  • Publisher: 医薬ジャーナル社
• [Book] 好酸球性消化管疾患のトピックス, 好酸球増多症候群と好酸球性消化管疾患 (2013)
  • Author(s): 森山智彦, 江崎幹宏, 加藤光次, 竹中克斗, 一瀬理沙, 熊谷好晃, 平橋美奈子, 松本主之
  • Total Pages: 10
  • Publisher: 医学書院
• [Book] 第12回国際悪性リンパ腫会議報告 (2013)
  • Author(s): 加藤 光次
  • Total Pages: 3
  • Publisher: メディカルレビュー社