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Development of infection control system of multi-drug resistant bacteria from overseas

Research Project

Project/Area Number 25461522
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Infectious disease medicine
Research InstitutionTokyo Medical University

Principal Investigator

MIZUNO YASUTAKA  東京医科大学, 医学部, 准教授 (80287292)

Co-Investigator(Kenkyū-buntansha) MATSUMOTO Tetsuya  東京医科大学, 医学部, 教授 (10256688)
YAMAGUCHI Tetsuo  東京医科大学, 医学部, 兼任助教 (10408239)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords輸入感染症 / 薬剤耐性菌 / 渡航関連感染症 / 医療関連感染対策 / サーベイランス / 多剤耐性菌 / 国際情報交換 / シンガポール / インド / 南東アジア
Outline of Final Research Achievements

To clarify the characteristics associated with multi-drug resistant bacteria colonization in Japanese travellers, faecal culture tests were performed before departure and at return in Japanese travellers. Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) was detected half of travelers. This study demonstrated that staying abroad increased the risk of multidrug-resistant organism infection, especially in developing countries, primarily in South Asia. For multidrug-resistant organisms, measures against healthcare-associated infections and recognition of overseas-acquired infections are important. Attention should be focused especially on people returning from high-risk areas.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (11 results)

All 2016 2015 2014 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (10 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results)

  • [Journal Article] A first case of New Delhi metallo-β-lactamase-7 in an Escherichia coli ST648 isolate in Japan2014

    • Author(s)
      Mizuno Y, Yamaguchi T, Mastumoto T.
    • Journal Title

      Journal of Infection and Chemotherapy

      Volume: 20 Issue: 12 Pages: 814-816

    • DOI

      10.1016/j.jiac.2014.08.009

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 輸入感染症の感染対策2016

    • Author(s)
      水野 泰孝
    • Organizer
      第53回日本眼感染症学会 ICD講習会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2016-07-03
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 輸入感染症としての薬剤耐性菌2016

    • Author(s)
      水野 泰孝
    • Organizer
      第8回 臨床熱帯感染症研究会
    • Place of Presentation
      奈良商工会議所大ホール
    • Year and Date
      2016-02-27
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Multidrug-Resistant Organism Infection Acquired Overseas: A Prospective Study in Japanese Travelers2015

    • Author(s)
      Yasutaka Mizuno, Tetsuo Yamaguchi, Tetsuya Matsumoto
    • Organizer
      Interscience Conference of Antimicrobial Agents and Chemotherapy 2015,
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2015-09-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 日本人渡航者の海外における多剤耐性菌感染状況2015

    • Author(s)
      水野泰孝、山口哲央、松本哲哉
    • Organizer
      第89回日本感染症学会総会・学術講演会
    • Place of Presentation
      京都
    • Year and Date
      2015-04-17
    • Related Report
      2014 Research-status Report
  • [Presentation] Global distribution of CTX-M-type resistant bacteria isolated from Japanese overseas travelers.2014

    • Author(s)
      Mizuno Y, Yamaguchi T, Matsumoto T.
    • Organizer
      54th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2014-09-06 – 2014-09-09
    • Related Report
      2014 Research-status Report
  • [Presentation] New Delhi Metallo-β-lactamase (NDM) producing Enterobacteriaceae brought to Japan by healthy traveler2014

    • Author(s)
      Yasutaka Mizuno, Tetsuo Yamaguchi, Tetsuya Matsumoto
    • Organizer
      10th Asia Pacific Travel Health Conference
    • Place of Presentation
      Ho Chi Minh City, Vietnam
    • Related Report
      2013 Research-status Report
  • [Presentation] NDM-1産生菌が健康な海外渡航者によって持ち込まれた事例2014

    • Author(s)
      水野 泰孝, 山口 哲央, 松本 哲哉
    • Organizer
      第88回日本感染症学会学術講演会総会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] 海外渡航者における多剤耐性菌保有状況

    • Author(s)
      水野 泰孝, 山口 哲央, 松本 哲哉
    • Organizer
      第87回日本感染症学会学術講演会総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Research-status Report
  • [Presentation] 輸入感染症と感染対策・細菌感染症

    • Author(s)
      水野 泰孝
    • Organizer
      第87回日本感染症学会学術講演会総会
    • Place of Presentation
      横浜
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Global spread of multi-drug resistant organism due to international travel.

    • Author(s)
      Yasutaka Mizuno, Tetsuo Yamaguchi, Tetsuya Matsumoto
    • Organizer
      53rd ICAAC
    • Place of Presentation
      Denver, CO, USA
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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