Development of an effective intervention method for childhood metabolic syndrome in terms of the incretin system
| Project/Area Number |
25461551
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Tottori University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KANZAKI SUSUMU 鳥取大学, 医学部, 教授 (90224873)
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| Research Collaborator |
KIMUARA SHINJI
KANAYAMA SHUNSUKE
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 小児肥満 / メタボリックシンドローム / 食事摂取量 / 多価不飽和脂肪酸 / インクレチン経路 / 不飽和脂肪酸 / インクレチン / 食物嗜好 |
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| Outline of Final Research Achievements |
There was no difference in the degree of obesity between children with higher and lower dietary intake of n-3 polyunsaturated fatty acids. The children with higher intake of n-3 polyunsaturated fatty acids showed higher protein (esp. animal protein) daily intake in contrast with a lower carbohydrate energy ratio. It is emphasized that a tailor-made, that is, based on the individual characteristics of food preference and dietary intake pattern, intervention should be provided upon dietary guidance for obese children, instead of instructing only energy reduction.
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Report
(4 results)
Research Products
(25 results)
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[Journal Article] Heterozygous nonsense mutations near the C-terminal region of IGF1R in two patients with small-for-gestational-age-related short stature.2015
Author(s)
Fujimoto M, Kawashima Sonoyama Y, Hamajima N, Hamajima T, Kumura Y, Miyahara N, Nishimura R, Adachi K, Nanba E, Hanaki K, Kanzaki S.
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Journal Title
Clin Endocrinol (Oxf)
Volume: 83(6)
Issue: 6
Pages: 834-41
DOI
Related Report
Peer Reviewed
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[Journal Article] Familial short stature is associated with a novel dominant-negative heterozygous insulin-like growth factor 1 receptor (IGF1R) mutation2014
Author(s)
Kawashima Y, Hakuno F, Okada SI, Hotsubo T, Kinoshita T, Fujimoto M, Nishimura R, Fukushima T, Hanaki K, Takahashi SI, Kanzaki S
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Journal Title
Clinical Endocrinology (Oxf)
Volume: Epub ahead of print
Issue: 2
Pages: 1-3
DOI
Related Report
Peer Reviewed
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