Schizophrenia and oligodendrocyte; roles of hnRNPC1 and 2
Project/Area Number |
25461756
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Psychiatric science
|
Research Institution | University of Fukui |
Principal Investigator |
Iwata Keiko 福井大学, 子どものこころの発達研究センター, 特命助教 (30415088)
|
Co-Investigator(Kenkyū-buntansha) |
MATSUZAKI Hideo 福井大学, 子どものこころの発達研究センター, 教授 (00334970)
MANABE Takayuki 中京学院大学, 看護学部, 教授 (90382283)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | oligodendrocyte / schizophrenia / hnRNPC / cell line / 神経科学 / 国際情報交換 / 統合失調症 / オリゴデンドロサイト / hnRNP C1/C2 |
Outline of Final Research Achievements |
The aim of this project is elucidation of pathophysiology of schizophrenia regarding myelination abnormality. We found that the expression change of hnRNP C2 effected on the expression of a myelination gene. Our findings suggest the involvement of the molecule in myelination and the pathophysiology of schizophrenia.
|
Report
(4 results)
Research Products
(6 results)