Application of paired pulse TMS tests to neuropsychiatric disorders
Project/Area Number |
25461767
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Psychiatric science
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Research Institution | Osaka University |
Principal Investigator |
IWASE MASAO 大阪大学, 医学(系)研究科(研究院), 講師 (60362711)
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Co-Investigator(Kenkyū-buntansha) |
ISHII RYOUHEI 大阪大学, 大学院医学系研究科, 助教 (40372619)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 単発・二連発磁気刺激 / GABA / 統合失調症 / 電気けいれん療法 / てんかん |
Outline of Final Research Achievements |
We developed a test protocol which could shorten testing time to reduce psychological stress of neuropsychiatric patients. We could not gather sufficient number of data to reach final conclusions so far due to a breakdown of transcranial magnetic stimulation apparatus. We also gather clinical data including electroencephalograph (EEG). EEG analyses revealed abnormal neural functional connectivities in patients with dementia and the utility for prediction of shunt operation effect in patients with idiopathic normal pressure hydrocephalus. We have repoted these results in foreign scientific journals.
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Report
(4 results)
Research Products
(52 results)
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[Journal Article] Dissociative experiences in epilepsy: effects of epilepsy-related factors on pathological dissociation.2015
Author(s)
Hara K, Adachi N, Akanuma N, Ito M, Okazaki M, Matsubara R, Adachi T, Ishii R, Kanemoto K, Matsuura M, Hara E, Kato M, Onuma T.
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Journal Title
Epilepsy Behav
Volume: 44
Pages: 185-91
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Emotion Regulation of Neuroticism: Emotional Information Processing Related to Psychosomatic State Evaluated by Electroencephalography and Exact Low-Resolution Brain Electromagnetic Tomography.2015
Author(s)
Ikeda S, Mizuno-Matsumoto Y, Canuet L, Ishii R, Aoki Y, Hata M, Katsimichas T, Pascual-Marqui RD, Hayashi T, Okamoto E, Asakawa T, Iwase M, Takeda M.
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Journal Title
Neuropsychobiology. 2015 Feb 27;71(1):34-41. [
Volume: 71
Pages: 34-41
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Association of cerebrospinal fluid tap-related oscillatory activity and shunt outcome in idiopathic normal-pressure hydrocephalus.2015
Author(s)
Ikeda S, Kazui H, Tanaka T, Ishii R, Aoki Y, Hata M, Canuet L, Yoshiyama K, Iwase M, Pascual-Marqui R, Takeda M.
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Journal Title
Psychogeriatrics. 2015 Sep;15(3):191-7.
Volume: 15
Issue: 3
Pages: 191-7
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Noninvasive prediction of shunt operation outcome in idiopathic normal pressure hydrocephalus.2015
Author(s)
Aoki Y, Kazui H, Tanaka T, Ishii R, Wada T, Ikeda S, Hata M, Canuet L, Katsimichas T, Musha T, Matsuzaki H, Imajo K, Kanemoto H, Yoshida T, Nomura K, Yoshiyama K, Iwase M, Takeda M
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Journal Title
Scientific reports
Volume: 5
Issue: 1
Pages: 1-5
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Frontal midline theta rhythm and gamma power changes during focused attention on mental calculation: an MEG beamformer analysis.2014
Author(s)
Ishii R, Canuet L, Ishihara T, Aoki Y, Ikeda S, Hata M, Katsimichas T, Gunji A, Takahashi H, Nakahachi T, Iwase M, Takeda M.
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Journal Title
Front Hum Neurosci
Volume: 8
Pages: 406-406
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Frontal midline theta rhythm and gamma power changes during focused attention on mental calculation: an MEG beamformer analysis.2014
Author(s)
Ishii R, Canuet L, Ishihara T, Aoki Y, Ikeda S, Hata M, Katsimichas T, Gunji A, Takahashi H, Nakahachi T, Iwase M, Takeda M.
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Journal Title
Front Hum Neurosci.
Volume: 8
Pages: 406-406
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Normalized power variance change between pre-ictal and ictal phase2013
Author(s)
Aoki Y, Ishii R, Iwase M, Ikeda S, Hata M, Canuet L, Imajo K, Tanaka M, Matsuzaki H, Musha T, Takeda M
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Journal Title
Conf Proc IEEE Eng Med Biol Soc
Volume: 2013
Pages: 437-440
DOI
Related Report
Peer Reviewed
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[Journal Article] EEG and Neuronal Activity Topography analysis can predict effectiveness of shunt operation in idiopathic normal pressure hydrocephalus patients.2013
Author(s)
Aoki Y, Kazui H, Tanaka T, Ishii R, Wada T, Ikeda S, Hata M, Canuet L, Musha T, Matsuzaki H, Imajo K, Yoshiyama K, Yoshida T, Shimizu Y, Nomura K, Iwase M, Takeda M
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Journal Title
Neuroimage Clin
Volume: 3
Pages: 522-530
DOI
Related Report
Peer Reviewed
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[Presentation] レビー小体型認知症におけるeLORETA-ICAによる安静時皮質回路活動量の検出とその脳機能との関連2015
Author(s)
青木 保典, 數井 裕光, Roberto D. Pascual-Marqui, 石井 良平, 岩瀬 真生, 畑 真弘, 池田 俊一郎, 鐘本 英輝, 佐藤 俊介, 鈴木 由希子, 吉山 顕次
Organizer
第45回日本臨床神経生理学会
Place of Presentation
大阪国際会議場
Year and Date
2015-11-05
Related Report
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[Presentation] ELORETA-ICA resting state network activities of Dementia with Lewy bodies and their association with symptoms2015
Author(s)
"Yasunori Aoki, Hiroaki Kazui, Roberto D. Pascual-Marqui, Ryouhei Ishii, Masao Iwase, Kenji Yoshiyama, Hata Masahiro, Kaoru Imajo, Haruyasu Matsuzaki, Toshimitsu Musha "
Organizer
Annual Conference on Clinical Neurophysiology and Neuroimaging 2015-Joint Meeting of ECNS, ISNIP and ISBET, Munich, 2015.9.9-13
Place of Presentation
Munich(Germany)
Year and Date
2015-09-09
Related Report
Int'l Joint Research
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[Presentation] Symposium 13: EEG biomarker for shunt operation outcome in idiopathic normal pressure hydrocephalus2015
Author(s)
"Ryouhei Ishii, Yasunori Aoki, Hiroaki Kazui, Toshihisa Tanaka, Hata Masahiro, Leonides Canuet, Toshimitsu Musha, Haruyasu Matsuzaki, Kaoru Imajo, Kenji Yoshiyama, Masao Iwase "
Organizer
Annual Conference on Clinical Neurophysiology and Neuroimaging 2015-Joint Meeting of ECNS, ISNIP and ISBET, Munich, 2015.9.9-13
Place of Presentation
Munich(Germany)
Year and Date
2015-09-09
Related Report
Int'l Joint Research
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[Presentation] Forehead NIRS signal cahnges during Sternberg's task in schizophrenia2013
Author(s)
Masao Iwase, Michiyo Azechi, Koji Ikezawa, Ryouhei Ishii, Hidetoshi Takahashi, Takayuki Nakahachi, Leonides Canuet, Yasunori Aoki, Shunichir Ikeda, Masahiro Hata, Hiroaki Kazui, Motoyuki Fukumoto, Kazutaka Ohi, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Ryota Hashimoto, Masatoshi Takeda
Organizer
Neuro2013
Place of Presentation
京都市
Related Report
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[Presentation] Tissue oxygen index of NIRS forehead signals during performing frontal lobe tasks in schizophrenia2013
Author(s)
Masao Iwase, Michiyo Azechi, Koji Ikezawa, Ryouhei Ishii, Hidetoshi Takahashi, Takayuki Nakahachi, Leonides Canuet, Yasunori Aoki, Shunichir Ikeda, Masahiro Hata, Hiroaki Kazui, Motoyuki Fukumoto, Kazutaka Ohi, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Ryota Hashimoto, Masatoshi Takeda
Organizer
The 11th World Congress of the WFSBP
Place of Presentation
Kyoto
Related Report
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[Presentation] Source localization and functional connectivity during the emotional information processing under the psychosomatic states2013
Author(s)
Shunichiro Ikeda, Ryouhei Ishii, Yasunori Aoki, Masahiro Hata, Masao Iwase, Roberto Pascual-Marqui, Yuko Mizuno-Matsumoto, Takuto Hayashi, Eika Okamoto, Tetsuya Asakawa, Masatoshi Takeda
Organizer
The 11th World Congress of the WFSBP
Place of Presentation
Kyoto
Related Report
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[Presentation] Forehead NIRS signals during Sternberg's task in schizophrenia2013
Author(s)
Masao Iwase, Michiyo Azechi, Koji Ikezawa, Ryouhei Ishii, Hidetoshi Takahashi, Takayuki Nakahachi, Leonides Canuet, Yasunori Aoki, Shunichir Ikeda, Masahiro Hata, Hiroaki Kazui, Motoyuki Fukumoto, Kazutaka Ohi, Hidenaga Yamamori, Michiko Fujimoto, Yuka Yasuda, Ryota Hashimoto, Masatoshi Takeda
Organizer
The 11th World Congress of the WFSBP
Place of Presentation
Kyoto
Related Report
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[Presentation] 前頭部2ch-NIRS信号の精神科診断への応用可能性の限界2013
Author(s)
岩瀬真生, 疇地道代, 池澤浩二, 石井良平, 高橋秀俊, 中鉢貴行, レオニデス・カヌエト, 青木保典, 池田俊一郎, 畑真弘, 数井裕光, 福本素由己, 大井一高, 藤本美智子, 山森英長, 安田由華, 橋本亮太, 武田雅俊
Organizer
第43回日本臨床神経生理学会
Place of Presentation
高知市
Related Report
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[Presentation] アルツハイマー病患者の脳波によるLORETA-connectivity解析による検討2013
Author(s)
畑 真弘, 石井 良平, 青木 保典, 池田 俊一郎, 岩瀬 真生, 鐘本 英輝, 清水 芳郎, 野村 慶子, 吉山 顕次, 数井 裕光, ロベルト・パスカルマルキー , 武田 雅俊
Organizer
第43回日本臨床神経生理学会
Place of Presentation
高知市
Related Report
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[Presentation] 正常圧水頭症における髄液排除試験による脳機能変化の脳波NAT解析による検出2013
Author(s)
青木 保典, 數井 裕光, 石井 良平, 岩瀬 真生, 武者 利光, 松崎 晴康, 今城 郁, 和田 民樹, 池田 俊一郎, 畑 真弘, 清水 芳郎, 山本 大介, 杉山 博通, 野村 慶子, 吉山 顕次, 武田 雅俊
Organizer
第43回日本臨床神経生理学会
Place of Presentation
高知市
Related Report
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