Brain network analysis of autistic spectrum disorder using EEG LORETA analysis

• Project/Area Number: 25461769
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Osaka University
• Principal Investigator: ISHII RYOUHEI 大阪大学, 医学(系)研究科(研究院), 助教 (40372619)
• Co-Investigator(Kenkyū-buntansha): IWASE Masao 大阪大学, 医学系研究科, 講師 (60362711)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
• Keywords: 脳波 / 脳磁図 / コネクティビティ / 発達障害 / 認知症 / 独立成分分析 / LORETA / コネクティビティ解析 / 自閉症スペクトラム障害 / 周波数解析

Outline of Final Research Achievements

We've developed the new methods to analyse the brain connectivity using EEG and MEG signals by using eLORERTA analysis. As our first step, we analysed the resting state network of the normal controls and abnormal connectivity among dementia patients.

Research Products

• [Journal Article] Noninvasive prediction of shunt operation outcome in idiopathic normal pressure hydrocephalus. (2015)
  • Author(s): Aoki Y, Kazui H, Tanaka T, Ishii R, Wada T, Ikeda S, Hata M, Canuet L, Katsimichas T, Musha T, Matsuzaki H, Imajo K, Kanemoto H, Yoshida T, Nomura K, Yoshiyama K, Iwase M, Takeda M
  • Journal Title: Scientific reports Volume: 5 Issue: 1 Pages: 1-5
  • DOI: 10.1038/srep07775
  • Peer Reviewed / Open Access
• [Journal Article] Frontal midline theta rhythm and gamma power changes during focused attention on mental calculation: an MEG beamformer analysis. (2014)
  • Author(s): Ishii R, Canuet L, Ishihara T, Aoki Y, Ikeda S, Hata M, Katsimichas T, Gunji A, Takahashi H, Nakahachi T, Iwase M, Takeda M.
  • Journal Title: Front Hum Neurosci Volume: 8 Pages: 406-406
  • DOI: 10.3389/fnhum.2015.00031
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] EEG biomarkers of NeuroAIDS. (2014)
  • Author(s): Ishii R, Canuet L.
  • Journal Title: Clin Neurophysiol Volume: 125 Issue: 6 Pages: 1075-1076
  • DOI: 10.1016/j.clinph.2014.01.019
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Global complexity and cognitive reserve in MCI. (2014)
  • Author(s): Ishii R, Canuet L.
  • Journal Title: Clin Neurophysiol Volume: 125 Issue: 4 Pages: 653-654
  • DOI: 10.1016/j.clinph.2013.10.015
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] EEG Connectome: a new candidate for endophenotypes (2013)
  • Author(s): Ishii R, Canuet L
  • Journal Title: Clin Neurophysiol Volume: 124 Issue: 12 Pages: 2289-2290
  • DOI: 10.1016/j.clinph.2013.07.011
  • Peer Reviewed
• [Journal Article] EEG and Neuronal Activity Topography analysis can predict effectiveness of shunt operation in idiopathic normal pressure hydrocephalus patients. (2013)
  • Author(s): Aoki Y, Kazui H, Tanaka T, Ishii R, Wada T, Ikeda S, Hata M, Canuet L, Musha T, Matsuzaki H, Imajo K, Yoshiyama K, Yoshida T, Shimizu Y, Nomura K, Iwase M, Takeda M
  • Journal Title: Neuroimage Clin Volume: 3 Pages: 522-530
  • DOI: 10.1016/j.nicl.2013.10.009
  • Peer Reviewed
• [Journal Article] Frequency diversity of posterior oscillatory activity in human revealed by spatial filtered MEG. (2013)
  • Author(s): Ishii R, Canuet L, Aoki Y, Ikeda S, Hata M, Takahashi H, Nakahachi T, Gunji A, Iwase M, Takeda M.
  • Journal Title: J Integr Neurosci. Volume: 12 Issue: 03 Pages: 343-353
  • DOI: 10.1142/s0219635213500209
  • Peer Reviewed
• [Journal Article] Non-parametric permutation thresholding for adaptive nonlinear (2013)
  • Author(s): Ishii R, Canuet L, Aoki Y, Ikeda S, Hata M, Iwase M, Takeda M
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc Volume: 2013 Pages: 4807-4810
  • DOI: 10.1109/embc.2013.6610623
  • Peer Reviewed
• [Journal Article] Normalized power variance change between pre-ictal and ictal phase (2013)
  • Author(s): Aoki Y, Ishii R, Iwase M, Ikeda S, Hata M, Canuet L, Imajo K, Tanaka M, Matsuzaki H, Musha T, Takeda M
  • Journal Title: Conf Proc IEEE Eng Med Biol Soc Volume: 2013 Pages: 437-440
  • DOI: 10.1109/embc.2013.6609530
  • Peer Reviewed
• [Presentation] アルツハイマー病の髄液所見と脳波律動の関連について -eLORETAによる検討- (2014)
  • Author(s): 畑 真弘、田中 稔久、数井 裕光、石井 良平、池田 俊一郎、青木 保典、佐藤 俊介、鈴木 由希子、鐘本 英輝、吉山 顕次、岩瀬 真生、武田 雅俊
  • Organizer: 第44回日本臨床神経生理学術大会
  • Place of Presentation: 福岡市
  • Year and Date: 2014-11-21