| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Outline of Final Research Achievements |
The role of dopamine transporter (DAT) function in the delusion and hallucination was examined by DAT positron emission tomography (PET). Seventeen geriatric patients with delusional disorder, 8 geriatric patients with schizophrenia, 12 geriatric healthy subjects, 2 young patients with delusional disorder, 6 young patients with schizophrenia and 9 young healthy controls were participated. DAT binding potential (BP) was examined by DAT-PET to compare the DAT function of each groups. Compared to geriatric healthy controls, geriatric patients with delusional disorder showed significantly lower DAT-BP. These results indicated the possibility that the decreased DAT function takes part in the mechanism of delusional disorder in old age period.
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