Regional Myocardial 3-Dimensional Rotational Motion Analysis with Cine MRI, Cardiac MDCT, and Myocardial Tagging.

• Project/Area Number: 25461800
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Tohoku University
• Principal Investigator: Saito Haruo 東北大学, 医学(系)研究科(研究院), 教授 (90170521)
• Co-Investigator(Renkei-kenkyūsha): HONMA NORIYASU 東北大学, 大学院医学系研究科, 教授 (30282023)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 心臓 / 磁気共鳴画像 / 回転運動 / 磁気共鳴画像（MRI)

Outline of Final Research Achievements

Regional myocardial rotational motion analyzed with cine MRI by following up the track of characteristic points on the intimal or the epicardial surface of left ventricle was almost equivalent to that with myocardial tagging images by following up the track of the intersections of grid-like tags on the left ventricular myocardium. Individual differences of longitudinal regional myocardial motion made it difficult to expand 2D motion analysis analyses to 3D ones. 2D regional myocardial motion analysis of patients with pulmonary hypertension demonstrated the presence of reduced regional myocardial motion segments even in the cases with normal global left ventricular motion.

Research Products

• [Journal Article] The prevalence of morphological changes in the thoracolumbar spine on whole-spine computed tomographic images (2014)
  • Author(s): Nakajima A, Usui A, Hosokai Y, Kawasumi Y, Abiko K, Funayama M, Saito H.
  • Journal Title: Insights Imaging. Volume: 5 Issue: 1 Pages: 77-83
  • DOI: 10.1007/s13244-013-0286-0
  • Peer Reviewed / Open Access
• [Presentation] Improvement of Left Ventricular Strain with Reduction of Mean Pulmonary Arterial Pressure in Chronic Thromboembolic Pulmonary Hypertension (2016)
  • Author(s): Tomoyoshi Kimura T, Ota H, Yamanaka K, Nagasaka T, Sugimura K, Shimokawa H, Takase K, Saito H
  • Organizer: 第72回 放射線技術学会総会
  • Place of Presentation: 横浜、パシフィコ横浜
  • Year and Date: 2016-04-14
• [Presentation] Improvement of Left Ventricular Strain with Reduction of Mean Pulmonary Arterial Pressure in Chronic Thromboembolic Pulmonary Hypertension (2016)
  • Author(s): Tomoyoshi Kimura T, Ota H, Yamanaka K, Nagasaka T, Sugimura K, Shimokawa H, Takase K, Saito H
  • Organizer: 第80回 日本循環器病学会
  • Place of Presentation: 仙台、仙台国際センター
  • Year and Date: 2016-03-17
• [Presentation] Improvement of Left Ventricular Strain with Reduction of Mean Pulmonary Arterial Pressure in Pulmonary Hypertension: (2015)
  • Author(s): Kimura T, Ota H, Sugimura K, Yamanaka K, Nagasaka T, Shimokawa H, Takase K, Saito H
  • Organizer: ISMRM
  • Place of Presentation: Tronto, Canada
  • Year and Date: 2015-05-30 – 2015-06-05
• [Presentation] Improvement of Left Ventricular Strain with Reduction of Mean Pulmonary Arterial Pressure in Pulmonary Hypertension: Treatment Effect Independent of Right Ventricular Volumetric Parameters. (2015)
  • Author(s): Tomoyoshi Kimura T, Ota H, Yamanaka K, Nagasaka T, Sugimura K, Shimokawa H, Takase K, Saito H
  • Organizer: 23rdInternational Society for Magentic Resonance in Medicine
  • Place of Presentation: Toronto, Canada
  • Year and Date: 2015-05-30
  • Int'l Joint Research
• [Presentation] .A feasibility study of dual contrast blood image (DCBI) using balanced steady state free precession (B-SSFP) with phase sensitive inversion recovery (PSIR). (2015)
  • Author(s): Yoshida T, Katsumata Y, Furukawa Y, Nozaki M, Nagasaki T, Hirano M, Kawauch N, Shirai T, Saito H.
  • Organizer: European Congress of Radiology
  • Place of Presentation: Vienna, Austria
  • Year and Date: 2015-03-04 – 2015-03-08
• [Presentation] A preliminary study of 3D Dual Contrast Blood image using Balanced-steady state free precession with Phase sensitive inversion recovery. (2014)
  • Author(s): Yoshida T, Katsumata Y, Furukawa Y, Tsuchiya H, Kato Y, Kawauchi N, Saito H.
  • Organizer: 第42回日本磁気共鳴医学会大会
  • Place of Presentation: 京都 ホテルグランヴィア京都
  • Year and Date: 2014-09-18 – 2014-09-20
• [Presentation] MOLLI法における左心室心筋T1値の部位による差について-FAの違いからみた検討- (2014)
  • Author(s): 木村 智圭,大田 英揮,永坂 竜男,山中 一臣,佐々木 博信,根本 整,上野結衣,上野裕理,小森 芳秋,高瀬 圭,斉藤 春夫
  • Organizer: 第42回日本磁気共鳴医学会大会
  • Place of Presentation: 京都 ホテルグランヴィア京都
  • Year and Date: 2014-09-18 – 2014-09-20
• [Presentation] Influence on Cardiac Evaluation Image due to Different Heart Rate setting using 3D-CT : A Kinetic Cardiac Phantom Study (2014)
  • Author(s): Kozakai M, Hosokai Y, Abe M, Konno T, Sano H, Tanae S, Usui A, Kawasumi Y, Kaga Y, Saito H.
  • Organizer: SCCT Hawaii
  • Place of Presentation: The Island of Hawaii, USA