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Performance evaluation of lung cancer CT screening CAD and developmant

Research Project

Project/Area Number 25461803
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionNiigata University

Principal Investigator

WADA SHINICHI  新潟大学, 医歯学系, 教授 (80105519)

Co-Investigator(Kenkyū-buntansha) OHKUBO Masaki  新潟大学, 医歯学系, 教授 (10203738)
Research Collaborator MATSUMOTO Toru  
MURAO Kohei  
MARASINGHE Janaka C  
KOBAYASHI Hajime  
YOSHIDA Akifumi  
GOUDO Makoto  
NARITA Akihiro  
SUGAWARA Hideyoshi  
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
KeywordsCAD / Quality Assurance / Point Spread Function / CT(Computed Tomography) / Virtual nodule / Lung cancer CT screening / 3D-PSF / Low dose CT screening / point spread function / quality assurance of CAD / virtual nodule / lung cancer CT screening / Low Dose CT Screening / Lung Cancer CT Screening / Quality Assurance of CAD / 3D-PSF / Virtual Nodule / ROC / CT screening / PSF / CAD performance / lung cancer
Outline of Final Research Achievements

AAPM-CADSC have published the CAD- Quality Assurance (QA) guideline in Medical Physics recently. We also believe the study of CAD-QA is essential to establish the high quality lung cancer CT screening. The purpose of this study is to develop a method of QA of lung cancer CT screening CAD systems. The research strategy is aimed to cover the image quality characteristic problem caused by a variety of CT image quality due to the difference of the CT manufactures, image acquisition and reconstruction parameters. PSF and SSP were measured to know the 3D-PSF. Using 3D-PSF the virtual nodules were generated. The following 4 issues were discussed in applying the virtual nodule for CAD-QA, (1) Verification of PSF-based virtual nodule method using a CT screening database, (2) virtual nodule application to CAD study as a performance evaluation method, (3) study for the sophistication of the Virtual Nodule,(4) robustness evaluation of CAD performance of algorithm differences.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (26 results)

All 2016 2015 2014 2013

All Journal Article (12 results) (of which Open Access: 3 results,  Peer Reviewed: 4 results,  Acknowledgement Compliant: 1 results) Presentation (14 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] 3D-PSF模擬結節を用いた胸部CT-CADの性能評価の研究2016

    • Author(s)
      郷戸允, 大久保真樹,成田啓廣,菅原秀賢,村尾晃平,松本徹,和田真一
    • Journal Title

      CT検診

      Volume: 23 Pages: 30-30

    • Related Report
      2015 Annual Research Report
  • [Journal Article] 肺がん検診CTにおけるCADの性能評価を目的とした結節様被写体関数の作成に関する研究.2016

    • Author(s)
      Akihiro Narita, Masaki Ohkubo and Shinichi Wada
    • Journal Title

      医学物理

      Volume: 36-sup.1 Pages: 126-126

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Accurate volume measurement for lung nodule in CT image by deconvolution method.2016

    • Author(s)
      Hideyoshi Sugawara,Akihiro Narita, Masaki Ohkubo and Shinichi Wada
    • Journal Title

      医学物理

      Volume: 36-sup.1 Pages: 127-127

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Generateing Nodule-Like Object Function for CAD Performance Evaluation in Lung Cancer Screening:Fearsibility Study2016

    • Author(s)
      Akihiro Narita, Masaki Ohkubo, Shinichi Wada
    • Journal Title

      JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS

      Volume: 17 Issue: 3 Pages: 510-510

    • DOI

      10.1120/jacmp.v17i3.6370

    • Related Report
      2015 Annual Research Report
    • Open Access
  • [Journal Article] CT検診による肺がん死亡率低減‐医学物理からの寄与-2015

    • Author(s)
      和田 真一
    • Journal Title

      医学物理

      Volume: 35 Pages: 167-172

    • NAID

      130005162122

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Quality Assurance of lung cancer CT screening CAD system by applying PSF-based reference virtual nodule set.2015

    • Author(s)
      Janaka Marasinghe, Masaki Ohkubo, Hajime Kobayashi, Akifumi Yoshida, Kohei Murao, Toru Matsumoto,Shusuke Sone, Shinichi Wada
    • Journal Title

      EPOS-TM,Electronic Presentation Online System

      Volume: ECR-2015 Pages: 1-11

    • DOI

      10.1594/ECR2015/C-1125

    • Related Report
      2014 Research-status Report
    • Open Access
  • [Journal Article] 胸部CT検診CADのQAに関する研究:ファントム模擬結節によるvirtual nodule offsetの検証2015

    • Author(s)
      吉田皓文、大久保真樹、Marasinghe Janaka C、村尾晃平、松本徹、和田真一
    • Journal Title

      CT検診

      Volume: 22 Pages: 36-36

    • Related Report
      2014 Research-status Report
  • [Journal Article] Validation of using PSF^based virtual nodule to assess the basec performances of lung cancer CT screening CAD system.2014

    • Author(s)
      Janaka Marasinghe, Masaki Ohkubo, Hajime Kobayashi, Akifumi Yoshida, Kohei Murao, Toru Matsumoto,Shusuke Sone, Shinichi Wada
    • Journal Title

      Int J CAD

      Volume: 9 Issue: S1 Pages: 235-238

    • DOI

      10.1007/s11548-014-1034-8

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Feasible Method to Assess the Performance of a Lung Cancer CT Screening CAD System in Clinical Practice: Dependence on Nodule Size and Density2014

    • Author(s)
      Janaka C. Marasinghe, Masaki Ohkubo, Hajime Kobayashi, Kohei Murao, Toru Matsumoto, Shusuke Sone, Shinichi Wada
    • Journal Title

      International Journal of Medical Physics, Clinical Engineering and Radiation Oncology

      Volume: 3 Pages: 107-116

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Observer-independent nodule-detectability index for low-dose lung cancer screening CT: a pilot study.2013

    • Author(s)
      Ohkubo M, Wada S, Kanai S, Ishikawa K, Marasinghe JC, Matsumoto T.
    • Journal Title

      Radiological Physics and Technology

      Volume: 6 Issue: 2 Pages: 492-499

    • DOI

      10.1007/s12194-013-0225-2

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Accurate determination of CT point-spread-function with high precision.2013

    • Author(s)
      Kayugawa A, Ohkubo M, Wada S.
    • Journal Title

      Journal of Applied Clinical Medical Physics

      Volume: 14 Issue: 4 Pages: 216-226

    • DOI

      10.1120/jacmp.v14i4.3905

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] EVALUATION OF LUNG CT CAD PERFORMANCE BY USING PSF-BASED VIRTUAL NODULES:2013

    • Author(s)
      Janaka Marasinghe, Masaki Ohkubo, Hajime Kobayashi, Kohei Murao, Toru Matsumoto,,Shusuke Sone, Shinichi Wada
    • Journal Title

      Medical Physics International

      Volume: 1(2) Pages: 350-350

    • Related Report
      2013 Research-status Report
  • [Presentation] 肺がん検診CTにおけるCADの性能評価を目的とした結節様被写体関数の作成に関する研究.2016

    • Author(s)
      Akihiro Narita, Masaki Ohkubo and Shinichi Wada
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜 会議センター, (神奈川県横浜市)
    • Year and Date
      2016-04-14
    • Related Report
      2015 Annual Research Report
  • [Presentation] Accurate volume measurement for lung nodule in CT image by deconvolution method.2016

    • Author(s)
      Hideyoshi Sugawara,Akihiro Narita, Masaki Ohkubo and Shinichi Wada
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜 会議センター, (神奈川県横浜市)
    • Year and Date
      2016-04-12
    • Related Report
      2015 Annual Research Report
  • [Presentation] Generationg Nodule-Like Object Function for CAD Performance Evaluation in Lung Cancer Screening:Feasibility Study2016

    • Author(s)
      A Narita, M Ohkubo, S Wada
    • Organizer
      AAPM Spring Clinical Meeting 2016
    • Place of Presentation
      The Grand America Hotel, (Salt Lake City, UT, USA)
    • Year and Date
      2016-03-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 3D-PSF模擬結節を用いた胸部CT-CADの性能評価の研究2016

    • Author(s)
      郷戸允, 大久保真樹,成田啓廣,菅原秀賢,村尾晃平,松本徹,
    • Organizer
      第23回日本CT検診学会学術集会
    • Place of Presentation
      柏の葉カンファレンスセンター,三井ガーデンホテル (千葉県柏市)
    • Year and Date
      2016-02-12
    • Related Report
      2015 Annual Research Report
  • [Presentation] Reduction of Lung Cancer by disseminating CT screening-Action as a Medical Physicist2015

    • Author(s)
      和田 真一
    • Organizer
      第109回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜 会議センター, (神奈川県横浜市)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 胸部CT検診CADのQAに関する研究:ファントム模擬結節によるvirtual nodule offsetの検証2015

    • Author(s)
      吉田皓文、大久保真樹、Marasinghe Janaka C、村尾晃平、松本徹、和田真一
    • Organizer
      第22回日本CT検診学会学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2015-02-13 – 2015-02-14
    • Related Report
      2014 Research-status Report
  • [Presentation] Validation of using PSF^based virtual nodule to assess the basec performances of lung cancer CT screening CAD system.2014

    • Author(s)
      Janaka Marasinghe, Masaki Ohkubo, Hajime Kobayashi, Akifumi Yoshida, Kohei Murao, Toru Matsumoto,Shusuke Sone, Shinichi Wada
    • Organizer
      Validation of using PSF^based virtual nodule to assess the basec performances of lung cancer CT screening CAD system.
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2014-06-25 – 2014-06-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 胸部CT検診CAD性能評価におけるnodule offsetの影響2014

    • Author(s)
      Akifumi Yoshida,Masaki Ohkubo,Hajime Kobayashi,Marasinghe Janaka C,D.M.Janaka Nuwan,Kohei Murao,Toru Matsumoto,Shunsuke Sone, and Shinihi Wada
    • Organizer
      第107会日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-04-10 – 2014-04-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 肺がんCT検診認定技師によるCT異常所見検出と医師によるCT読影に関する研修-第1報;実験計画の概要と途中経過結果の報告2014

    • Author(s)
      潤間励子、村尾晃平、和田眞一、五味志保、津田雪裕、村松禎久、松本徹、花井耕造、長尾啓一
    • Organizer
      第21回日本CT検診学会学術集会
    • Place of Presentation
      千葉
    • Related Report
      2013 Research-status Report
  • [Presentation] 胸部CT検診CAD性能評価におけるnodule offsetの影響2014

    • Author(s)
      吉田皓文,大久保真樹,小林元, Marasinghe Janaka C,D.M.Janaka Nuwan,村尾晃平, 松本徹, 曽根脩輔, 和田真一
    • Organizer
      第107回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Related Report
      2013 Research-status Report
  • [Presentation] Validation of using PSF-based virtual nodules to assess the basic performances of lung cancer CT screening CAD system.2014

    • Author(s)
      J C Marasinghe, M Ohkubo, H Kobayashi, A Yosida, K Murao, T Matsumoto, S Sone, S Wada
    • Organizer
      CARS2014
    • Place of Presentation
      Fukuoka,Japan
    • Related Report
      2013 Research-status Report
  • [Presentation] CT装置の空間分解能に基づいたvirtual noduleの生成および胸部CT検診CADの性能評価への応用:ファントム結節との比較による検証2013

    • Author(s)
      小林元,大久保真樹, Marasinghe Janaka C, 村尾晃平, 松本徹, 曽根脩輔, 和田真一
    • Organizer
      第128回日本医学放射線学会北日本地方会
    • Place of Presentation
      新潟市
    • Related Report
      2013 Research-status Report
  • [Presentation] EVALUATION OF LUNG CT CAD PERFORMANCE BY USING PSF-BASED VIRTUAL NODULES:2013

    • Author(s)
      Janaka Marasinghe, Masaki Ohkubo, Hajime Kobayashi, Kohei Murao, Toru Matsumoto,Shusuke Sone, Shinichi Wada
    • Organizer
      ICMP2013
    • Place of Presentation
      Brighton,UK
    • Related Report
      2013 Research-status Report
  • [Presentation] PSF-based virtual nodule を用いた胸部 CT 検診 CAD 性能評価法の研究:ファントム模擬結節との比較による検証2013

    • Author(s)
      小林元,大久保真樹, Marasinghe Janaka C, 村尾晃平, 松本徹, 曽根脩輔, 和田真一
    • Organizer
      第106回日本医学物理学会学術大会
    • Place of Presentation
      大阪市
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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