| Project/Area Number |
25461806
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KIMURA Hirohiko 福井大学, 医学部, 教授 (10242596)
KUROKAWA Tetsuji 福井大学, 医学部, 准教授 (60334835)
FUJIWARA Yasuhiro 熊本大学, 大学院生命科学研究部(保), 講師 (90422675)
KANAMOTO Masayuki 福井大学, 医学部附属病院, 診療放射線技師 (60730728)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | MRI / 子宮 / 腎臓 / 灌流画像 / 放射線 / Arterial spin labeling / 卵巣 |
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| Outline of Final Research Achievements |
In this project, we developed non-contrast enhanced perfusion MRI method (arterial spin labeling method: ASL-MRI) for abdominal organs. The tissue perfusions in kidneys measured with this ASL-MRI were validated by comparing nuclear imaging methods. Furthermore, we applied this method to placental polyps in uterus, and successfully depicted their tissue perfusions and therapeutic responses visually and semi-quantitatively. Although further technical development may be needed for more stable image acquisitions, this ASL-MRI method has clinical potential for non-invasive assessment of tissue perfusion in uterus and other abdominal organs.
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