Visualization of the deep perforating artery and related brain changes
Project/Area Number |
25461819
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Radiation science
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Research Institution | Kyoto University |
Principal Investigator |
Okada Tomohisa 京都大学, 医学(系)研究科(研究院), 准教授 (30321607)
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Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Akira 京都大学, 大学院医学研究科, 助教 (60525567)
KANAGAKI Mitsunori 京都大学, 大学院医学研究科, 助教 (50378676)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 深部灰白質穿通動脈 / MRアンギオグラフィ / レンズ核線条体動脈 / 高血圧 / 磁気共鳴画像 / 基底核穿通動脈 / TOF-MRA / FSBB-MRA / MRアンギオグラフィー / 深部灰白質穿通動脈枝 / FSBB / TOF |
Outline of Final Research Achievements |
This research targeted the perforating artery of the deep gray matter. Firstly, its visualization was successfully conducted using a new scan method of FSBB at 3T. The visualization was also confirmed on 7T. Secondly, its pathological changes caused by such factors as hypertension are under analysis now. Thirdly, for structural changes caused by the perforating artery, methodological validation was conducted on volumetry and T1 value quantitation. Diffusion tensor imaging was also conducted to investigate small structures in the brain. Moya-moya disease was selected as a representative case for a pathological condition related to the perforating artery and the investigational results was reported.
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Report
(4 results)
Research Products
(7 results)
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[Journal Article] Visualization of lenticulostriate arteries at 3T: Optimization of slice-selective off-resonance sinc pulse-prepared TOF-MRA and its comparison with flow-sensitive black-blood MRA.2014
Author(s)
Okuchi S, Okada T, Fujimoto K, Fushimi Y, Kido A, Yamamoto A, Kanagaki M, Dodo T, Mehemed TM, Miyazaki M, Zhou X, Togashi K.
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Journal Title
Academic Radiology
Volume: 21
Issue: 6
Pages: 812-6
DOI
Related Report
Peer Reviewed
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[Presentation] Brain Morphometry Reproducibility Analysis between Longitudinal and Cross-sectional Processing.2015
Author(s)
Maruguchi N, Fushimi Y, Okada T, Fujimoto K, Hinoda T, Yamamoto A, Okada T, Kido A, Sakashita N, Togashi K.
Organizer
European Society of Magnetic Resonance in Medicine and Biology.
Place of Presentation
Edinburgh, United Kingdom.
Year and Date
2015-10-01
Related Report
Int'l Joint Research
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