An investigation for clinical usefulness of FDG PET examination in the diagnosis of cardiac sarcoidosis.
| Project/Area Number |
25461830
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Ehime University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
Miyagawa Masao 愛媛大学, 医学部附属病院, 准教授 (90346685)
Ogimoto Akiyoshi 愛媛大学, 医学部附属病院, 准教授 (00403832)
Kido Teruhito 愛媛大学, 大学院医学系研究科, 講師 (50403837)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 心サルコイドーシス / FDG-PET |
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| Outline of Final Research Achievements |
In April 2012, the Japanese health insurance system approved reimbursement for FDG PET use to detect inflammation sites in cardiac sarcoidosis. In order to diagnose active inflammatory lesions in the myocardium, it is essential to highlight FDG uptake in the lesions and no physiological uptake in the normal myocardium. The Japanese Society of Nuclear Cardiology including our institution has developed the recommendations of the basic FDG PET procedure. However, complete suppression of physiological uptake in the normal myocardium in all patients has yet been reported. The present randomized-control study aimed to compare the suppression effects in 30 normal volunteers between a more than 18-h long fasting with a low-carbohydrate diet (LCD) and that with an additional use of heparin. The complete suppression of FDG uptake in the myocardium is visually and quantitatively achieved by the 18-h fasting with LCD preparation protocol. Use of heparin brings no added value to the protocol.
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Report
(4 results)
Research Products
(15 results)
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[Journal Article] Aortic prosthetic graft infection detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography.2015
Author(s)
Kono T, Ogimoto A, Iio C, Fujimoto K, Fujii A, Uetani T, Nagai T, Nishimura K, Inoue K, Suzuki J, Hiasa G, Okayama H, Okura T, Miyagawa M, Mochizuki T
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Journal Title
Int J Cardiol.
Volume: 203
Pages: 972-974
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Detection of Cardiac Involvement in Sarcoidosis: Assessment by Image Fusion with Delayed-Enhanced MRI and F-18 FDG PET/CT. Sientific Poster Presentarion2015
Author(s)
Yokoyama R, Miyagawa M, Yokoi T, Ogawa R, Tanabe Y, Fukuyama N, Nishiyama Y, Kido TO, Kido TE, Kurata A, Mochizuki T
Organizer
RSNA 101th Annual Meeting 2015
Place of Presentation
Chicago, USA
Year and Date
2015-11-29
Related Report
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[Presentation] Detection of Cardiac Involvement in Sarcoidosis: Assessment by Image Fusion with Delayed-Enhanced MRI and F-18 FDG PET/CT2015
Author(s)
Yokoyama R, Miyagawa M, Tanabe Y, Matsuda T, Nakamura M, Nishiyama Y, Kawaguchi N, Kido TO, Kido TE, Ogimoto A, Higaki J, Mochizuki
Organizer
第74回日本医学放射線学会総会
Place of Presentation
パシフィコ横浜 神奈川県横浜市
Year and Date
2015-04-16
Related Report
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[Presentation] 遅延造影MRIとFDG PET/CT融合画像によるサルコイドーシスの評価.2013
Author(s)
横山らみ, 宮川正男, 中村壮志, 松田卓也, 川口直人, 西山香子, 城戸倫之, 城戸輝仁, 菊池隆徳, 大木元明義, 望月輝一
Organizer
第53回日本核医学会学術総会
Place of Presentation
福岡国際会議場
Related Report
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