| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
In April 2012, the Japanese health insurance system approved reimbursement for FDG PET use to detect inflammation sites in cardiac sarcoidosis. In order to diagnose active inflammatory lesions in the myocardium, it is essential to highlight FDG uptake in the lesions and no physiological uptake in the normal myocardium. The Japanese Society of Nuclear Cardiology including our institution has developed the recommendations of the basic FDG PET procedure. However, complete suppression of physiological uptake in the normal myocardium in all patients has yet been reported. The present randomized-control study aimed to compare the suppression effects in 30 normal volunteers between a more than 18-h long fasting with a low-carbohydrate diet (LCD) and that with an additional use of heparin. The complete suppression of FDG uptake in the myocardium is visually and quantitatively achieved by the 18-h fasting with LCD preparation protocol. Use of heparin brings no added value to the protocol.
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