| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
There are several limitations in the conventional MRI imaging to evaluate spine and spinal cord pathology in vivo, we tried new MR imaging technique, non-Gaussian diffusion MR imaging (dMRI) to apply for clinical spine and spinal cord imaging. Other than brain, it was necessary to optimize the MR imaging parameters and data analysis methods for spine and spinal cord dMRI and new technique and analysis methods were added to our investigation, which was not expected before. Our results showed that non-Gaussian dMRI analysis provided the additional information of microstructural changes in the spine and spinal cord pathology (i.e. cervical spondylotic myelopathy), which conventional MR images did not revealed.
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