Imaging of anti-tumor agents induced apoptosis and tumor glucose metabolism in a mouse carcinogenesis model.

Research Project

Project/Area Number	25461853
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Radiation science
Research Institution	Kansai Medical University
Principal Investigator	KAWA Soukichi 関西医科大学, 医学部, 准教授 (30152896)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000) Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords	アポトーシス / アネキシンV / FDG
Outline of Final Research Achievements	We have established a technology subculturing H1299 derived from the human non-small cell lung cancer as a tumor cell line. After γ-ray external irradiation, it was calculated FDG uptake into cells and measured over time to the inside(Cin) or outside of the cell ratio (Cin / Cout) until after 120 minutes. FDG uptake into cells after irradiation was increased any groups over time. Uptake was reduced to the dose-dependent.

Report

(4 results)