Imaging of anti-tumor agents induced apoptosis and tumor glucose metabolism in a mouse carcinogenesis model.
| Project/Area Number |
25461853
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kansai Medical University |
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Principal Investigator |
KAWA Soukichi 関西医科大学, 医学部, 准教授 (30152896)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | アポトーシス / アネキシンV / FDG |
|---|
| Outline of Final Research Achievements |
We have established a technology subculturing H1299 derived from the human non-small cell lung cancer as a tumor cell line.
After γ-ray external irradiation, it was calculated FDG uptake into cells and measured over time to the inside(Cin) or outside of the cell ratio (Cin / Cout) until after 120 minutes. FDG uptake into cells after irradiation was increased any groups over time. Uptake was reduced to the dose-dependent.
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Report
(4 results)
Research Products
(4 results)
