| Project/Area Number |
25461876
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Mie University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
馬場 康貴 鹿児島大学, 医学部・歯学部附属病院, 講師 (00315409)
穴井 洋 奈良県立医科大学, 医学部, 非常勤講師 (00322371)
山門 亨一郎 兵庫医科大学, 医学部, 教授 (20263022)
高木 治行 三重大学, 医学部, 助教 (30378377)
中塚 豊真 三重大学, 医学部附属病院, 講師 (70303740)
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| Project Period (FY) |
2013-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 肝細胞癌 / ミリプラチン / ラジオ波凝固療法 / 肝動注化学療法 |
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| Outline of Final Research Achievements |
To prospectively evaluate the safety and outcomes of combination treatment of miriplratin-iodized-oil suspension injection and radiofrequency ablation in hepatocellular carcinoma, local tumor progression at 2-year,adverse event, feasibility, initial response, local tumor progression on tumor basis at 2-year, overall survival rate at 2-year,and progression free survival rate at 2-year were evaluated.
local tumor progression at 2-year was 6.2% (1.1%-18.2%）. Feasibility was 100%（37/37）. Initial response was 93.8％（30/32）. local tumor progression on tumor basis at 2-year was 5.6%（1.0%-16.3%). progression free survival rate at 2-year was 84.4%（71.9%-96.9%）.
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