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Development of new radioembolization using radioisotope labeled lipiodol for hepatocellular carcinoma

Research Project

Project/Area Number 25461894
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKansai Medical University

Principal Investigator

TANIGAWA Noboru  関西医科大学, 医学部, 教授 (90227215)

Co-Investigator(Kenkyū-buntansha) UTSUNOMIYA KEITA  関西医科大学, 医学部, 講師 (20193914)
KARIYA SHUJI  関西医科大学, 医学部, 准教授 (40368220)
KOHNO YUMIKO  関西医科大学, 医学部, 助教 (10598957)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords放射性同位元素 / 肝細胞癌 / 肝動脈塞栓術 / RI標識リピオドール
Outline of Final Research Achievements

Transarterial chemoembolization is essential for unresectable hepatocellular carcinoma. We developed new radioembolization using Y-90 labeled lipiodol. Treatment model was divided into three groups according to the embolic materials, that is, lipiodol group, Y-90 labeled lipiodol group, and no treatment group, and treatment effects were compared among the three groups. The rabbits treated with Y-90 labeled lipiodol got the longest term survival among the three groups. New radioembolization using Y-90 labeled lipiodol is thought to be effective and shown the result of which the additional effect is expected compared with the conventional embolization.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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