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Study on quantification and visualization of displacement of divided regions on patient positioning in heavy-ion therapy

Research Project

Project/Area Number 25461904
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionGunma University

Principal Investigator

Tashiro Mutsumi  群馬大学, 未来先端研究機構, 准教授 (60447274)

Research Collaborator KUBOTA Yoshiki  
HAYASHI Hayato  
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords放射線治療 / 重粒子線治療 / 患者位置決め / 複数体積マッチング / 粒子線治療 / 患者自動位置決め / CT / DRR / X線画像
Outline of Final Research Achievements

This study aims development of automatic patient positioning software for radiotherapy and further development of a function to quantify and visualize the displacement of separated parts in patient bodies by dividing the images. We developed a “Multi-Volume Matching” technique based on our 2D-3D patient positioning software. In this technique, a 3D-CT volume was divided into multi-volumes such as a volume of interest (VOI) and a base volume (BV). The VOI was segmented so as to include structure whose motion appears in X-ray images. Then, 2D-3D matching was processed using X-ray images and Digitally Reconstructed Radiographs, which were repeatedly generated by changing 3D positions and angles of VOI and BV independently to match most with the X-ray images. Using this technique, we could visualize and quantify the displacement of VOI, as well as bony structure of the base body.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (17 results)

All 2017 2016 2015 2014 2013

All Journal Article (8 results) (of which Peer Reviewed: 6 results,  Open Access: 4 results) Presentation (8 results) (of which Int'l Joint Research: 2 results,  Invited: 2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Margin estimation and disturbances of irradiation field in layer-stacking carbon-ion beams for respiratory moving targets2017

    • Author(s)
      Tajiri S, Tashiro M, Mizukami T, Tsukishima C, Torikoshi M, Kanai T
    • Journal Title

      Journal OF Radiation Research

      Volume: - Issue: 6 Pages: 840-848

    • DOI

      10.1093/jrr/rrx001

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Incidence, risk factors, and dose-volume relationship of radiation-induced rib fracture after carbon ion radiotherapy for lung cancer2016

    • Author(s)
      Abe T, Shirai K, Saitoh J, Ebara T, Shimada H, Tashiro M, Okano N, Ohno T, Nakano T
    • Journal Title

      Acta Oncol.

      Volume: 55 Issue: 2 Pages: 163-166

    • DOI

      10.3109/0284186x.2015.1088169

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Development of an automatic evaluation method for patient positioning error2015

    • Author(s)
      Kubota Y, Tashiro M, Shinohara A, Abe S, Souda S, Okada R, Ishii T, Kanai T, Ohno T, Nakano T
    • Journal Title

      J Appl Clin Med Phys

      Volume: 16 Issue: 4 Pages: 100-111

    • DOI

      10.1120/jacmp.v16i4.5400

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 6 Treatment Planning2015

    • Author(s)
      田代睦、島田博文、川嶋基敬
    • Journal Title

      RADIOISOTOPES

      Volume: 64 Issue: 6 Pages: 394-399

    • DOI

      10.3769/radioisotopes.64.394

    • NAID

      130005083518

    • ISSN
      0033-8303, 1884-4111
    • Related Report
      2015 Research-status Report
    • Open Access
  • [Journal Article] 8 Radiation Control and Protection2015

    • Author(s)
      田代睦、石居隆義
    • Journal Title

      RADIOISOTOPES

      Volume: 64 Issue: 6 Pages: 406-408

    • DOI

      10.3769/radioisotopes.64.406

    • NAID

      130005083517

    • ISSN
      0033-8303, 1884-4111
    • Related Report
      2015 Research-status Report
    • Open Access
  • [Journal Article] Dosimetric analysis between carbon ion radiotherapy and stereotactic body radiotherapy in stage I lung cancer2014

    • Author(s)
      T. Ebara, H. Shimada, H. Kawamura, K. Shirai, J. Saito, M. Kawashima, M. Tashiro, T. Ohno, T. Kanai, T. Nakano
    • Journal Title

      Anticancer Research

      Volume: 34 Pages: 5099-5104

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quantitative Evaluation of the Robustness of Beam Directions Based on Power Spectral Analysis of Water-Equivalent Path Length Image in Charged Particle Therapy2014

    • Author(s)
      H. Arimura, G. Kakiuchi, Y. Shioyama, S. Minohara, T. Nakamoto, K. Nakamura, H. Honda, M. Tashiro, T. Kanai, H. Hirata
    • Journal Title

      International Journal of Intelligent Computing in Medical Sciences & Image Processing

      Volume: 6 Issue: 1 Pages: 1-16

    • DOI

      10.1080/1931308x.2013.876163

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Technical approach to individualized respiratory-gated carbon-ion therapy for mobile organs2013

    • Author(s)
      M. Tashiro, T. Ishii, J. Koya, R. Okada, Y. Kurosawa, K. Arai, S. Abe, Y. Ohashi, H. Shimada, K. Yusa, T. Kanai, S. Yamada, H. Kawamura, T. Ebara, T. Ohno, T. Nakano
    • Journal Title

      Radiological Physics and Technology

      Volume: (in press) Issue: 2 Pages: 356-366

    • DOI

      10.1007/s12194-013-0208-3

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Evaluation of High-Precision Automatic Patient Positioning System with Fast Calculation in Carbon Ion Radiotherapy; Patient study2016

    • Author(s)
      H. Hayashi, Y. Kubota, S. Abe, S. Souda, R. Okada, T. Ishii, M. Tashiro, M. Torikoshi, T. Kanai, T. Ohno, T. Nakano
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-04-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] Evaluation of High-Precision Automatic Patient Positioning System in Carbon Ion Radiotherapy: Patient study of 5 sites2016

    • Author(s)
      H. Hayashi, Y. Kubota, S. Abe, S. Souda, R. Okada, M. Tashiro, M. Torikoshi, T. Kanai, T. Ohno, T. Nakano
    • Organizer
      3rd International Symposium of Gunma University Medical Innocation and 8th International Conference on Advanced Micro-Device Engineering
    • Place of Presentation
      桐生市市民文化会館
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a High-Precision Automatic Patient Positioning Software with Fast Calculation in Carbon Ion Therapy: Verification for Prostate Cancer Cases2015

    • Author(s)
      H Hayashi1, Y Kubota, S Abe, S Souda, R Okada, T Ishii, M Tashiro, M Torikoshi, T Kanai, T Ohno, T Nakano
    • Organizer
      日本放射線腫瘍学会第28回学術大会
    • Place of Presentation
      ベイシア文化ホール・前橋商工会議所会館(群馬県・前橋市)
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
  • [Presentation] Development of an In-Vivo Spacer that Verifies Irradiated Position and Dose Distribution in Carbon Ion Therapy for Uterine Cervical Cancer2015

    • Author(s)
      Y Kubota, T Ohno, K Tsuda, M Tashiro, M Sakai, Y Hirano, N Okonogi, K Murata, S Noda, M Torikoshi, T Kanai, T Nakano
    • Organizer
      日本放射線腫瘍学会第28回学術大会
    • Place of Presentation
      ベイシア文化ホール・前橋商工会議所会館(群馬県・前橋市)
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
  • [Presentation] The influences of dose changes in beam angles for setup uncertainty and range uncertainty in carbon ion radiotherapy for prostate cancer patients2015

    • Author(s)
      Kubota Y, Kawamura H, Tashiro M, Matsumura A, Shimada H, Yusa K, Sato H, Kawahara M, Kanai T, Ohno T, Nakano T
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      Kyoto International Conference Center(京都府・京都市)
    • Year and Date
      2015-05-25
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 群馬大学重粒子線医学センター10年のあゆみ~装置・建屋を中心に~2014

    • Author(s)
      田代 睦
    • Organizer
      第50回群馬放射線腫瘍研究会
    • Place of Presentation
      群馬県高崎市
    • Year and Date
      2014-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Technical approach to individualized respiratory-gated carbon-ion therapy for mobile organs2014

    • Author(s)
      Mutsumi Tashiro, Takayoshi Ishii, Jun-ichi Koya, Ryosuke Okada, Yuji Kurosawa, Keisuke Arai, Satoshi Abe, Yoshiaki Ohashi, Hirofumi Shimada, Ken Yusa, Tatsuaki Kanai, Satoru Yamada, Hidemasa Kawamura, Takeshi Ebara, Tatsuya Ohno, Takashi Nakano
    • Organizer
      JRC2014
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2014-04-13
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Respiratory motion management for carbon-ion therapy at GHMC2014

    • Author(s)
      Mutsumi Tashiro
    • Organizer
      The 2nd International Symposium of Gunma University Program for Leading Graduate Schools
    • Place of Presentation
      Maebashi, Gunma, Japan
    • Related Report
      2013 Research-status Report
    • Invited
  • [Patent(Industrial Property Rights)] 患者位置決め支援装置2017

    • Inventor(s)
      田代 睦、久保田佳樹、仁衡琢磨、蓮見将弘
    • Industrial Property Rights Holder
      群馬大学、ペンギンシステム株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-031732
    • Filing Date
      2017-02-23
    • Related Report
      2016 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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