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Conversion of the energy-subtracted CT number to electron density based on a single linear relationship

Research Project

Project/Area Number 25461908
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionNiigata University

Principal Investigator

Saito Masatoshi  新潟大学, 医歯学系, 教授 (40241583)

Co-Investigator(Renkei-kenkyūsha) Hayakawa Takahide  新潟大学, 医歯学系, 助教 (00377194)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2015: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2014: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywordselectron density / dual-energy CT / treatment planning
Outline of Final Research Achievements

To achieve accurate tissue inhomogeneity corrections in radiotherapy treatment planning, we have previously proposed a novel conversion of the energy-subtracted CT number to an electron density (ΔHU-ρe conversion). In the present study, we investigate an initial implementation of the ΔHU-ρe conversion method for a treatment planning system. Two radiotherapy plans were used to compare the reliabilities of dose calculations based on the novel ΔHU-ρe conversion and the conventional method. The ΔHU-ρe conversion generally offered superior reliability. Based on our results, ΔHU-ρe conversion appears to be a promising method of providing a reliable inhomogeneity correction in treatment planning for ill-conditioned scans.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2016 2015 2014 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 3 results) Presentation (2 results)

  • [Journal Article] Initial implementation of the conversion from the energy-subtracted CT number to electron density in tissue inhomogeneity corrections: An anthropomorphic phantom study of radiotherapy treatment planning2015

    • Author(s)
      Masayoshi Tsukihara, Yoshiyuki Noto, Ryuta Sasamoto, Takahide Hayakawa and Masatoshi Saito
    • Journal Title

      Medical Physics

      Volume: 42 Issue: 3 Pages: 1378-1388

    • DOI

      10.1118/1.4908207

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Technical Note: Relation between dual-energy subtraction of CT images for electron density calibration and virtual monochromatic imaging2015

    • Author(s)
      Masatoshi Saito
    • Journal Title

      Medical Physics

      Volume: 42 Issue: 7 Pages: 4088-4093

    • DOI

      10.1118/1.4921999

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Technical Note: Exploring the limit for the conversion of energy-subtracted CT number to electron density for high-atomic-number materials2014

    • Author(s)
      Masatoshi Saito, Masayoshi Tsukihara
    • Journal Title

      Medical Physics

      Volume: 41 Issue: 7 Pages: 071701-071701

    • DOI

      10.1118/1.4881327

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 電子密度校正のためのエネルギー差分CT画像と仮想単色CT画像との関係2016

    • Author(s)
      齋藤正敏
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-14
    • Related Report
      2015 Annual Research Report
  • [Presentation] Calculation of dose distribution in radiotherapy by conversion of energy subtracted CT number to electron density with dual energy CT

    • Author(s)
      Masayoshi Tsukihara, Yoshiyuki Noto, Takahide Hayakawa, Masatoshi Saito
    • Organizer
      日本医学物理学会第107回学術大会
    • Place of Presentation
      パシフィコ横浜(横浜市西区)
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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