Development of Ultrasound-Guided Non-Invasive Hyperthermia System

• Project/Area Number: 25461930
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Meiji University
• Principal Investigator: Kato Kazuo 明治大学, 理工学部, 教授 (80115104)
• Co-Investigator(Kenkyū-buntansha): Shindo Yasuhiro 東洋大学, 理工学部, 助教 (00553017)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000); Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: 空胴共振器 / ハイパーサーミア / 超音波画像診断装置 / 有限要素法 / 寒天ファントム / 電磁界解析 / 温度分布解析 / 超音波ガイド

Outline of Final Research Achievements

In this study, an ultrasound-guided non-invasive hyperthermia system using a resonant cavity was developed. Specifically, we developed a non-contact resonant cavity applicator using the ultrasound image device to find the position and size of the heated target. After achieving our original goal, we examined the possibility of measuring temperature distributions using ultrasound images. It was found that non-invasive 2-D temperature distributions were measured from the displacement of ultrasound images before and after heating.

Research Products

• [Journal Article] Development of resonant cavity applicator system with non-invasive measurement of temperature distributions (2016)
  • Author(s): Yuya Iseki, Takahiro Saito, Daisuke Anan, Eitaro Miura, Kazuo Kato
  • Journal Title: 12th International Congress of Hyperthermic Oncology Volume: ABSTRACT Pages: 159-159
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Development of Ultrasound-Guided Resonant Cavity Applicator System - Non-invasive Measurement of Temperature Distributions – (2015)
  • Author(s): YUYA ISEKI, KEITO NAKAMURA, DAISUKE ANAN, KAZUO KATO
  • Journal Title: Thermal medicine Volume: VOL. 31, NO.3 Pages: 13-26
  • NAID: 130005113129
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Heating Properties of the Resonant Cavity Applicator with Ultrasound Monitoring System for Effective Hyperthermia Treatments (2015)
  • Author(s): K. Nakamura, D. Anan, T. Matsushita, Y.Iseki, Y. Shindo, K. Kato, T. Uzuka and H. Takahashi
  • Journal Title: EuCAP2015 Volume: Proc.
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] A New Heating Control M ethod for Effective Hyperthermia Treatme nt of a Brain Tumor Using the Resonant Cavity Applicator with a Segmented Dielectric Bolus (2014)
  • Author(s): YUYA ISEKI, HIDEAKI TAKAHASHI, TAKEO UZUKA, KAZUO KATO
  • Journal Title: Thermal Medicine Volume: 30 Pages: 41-53
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Heating Control Method for Resonant Cavity Applicator Using Divided Type of Dielectric Bolus for Effective Hyperthermia Treatment (2013)
  • Author(s): Y. Iseki, Y. Shindo, M. Kubo, K. Watanabe, J. Arakawa, H. Takahashi, T. Uzuka and K. Kato
  • Journal Title: 2013 7th European Conference on Antennas and Propagation Volume: Proc. Pages: 1122-1126
  • Peer Reviewed
• [Journal Article] Heating Control Method of Resonant Cavity Applicator for Non-invasive Hyperthermia Treatment (2013)
  • Author(s): Y. Iseki, J. Arakawa, K. Watanabe, Y. Shindo and K. Kato
  • Journal Title: 2013 International Conference on Electromagnetics in Advanced Applications Volume: Proc. Pages: 328-331
  • Peer Reviewed
• [Journal Article] Temperature estimation of hyperthermia treatment with blood perfusion inside blood vessels (2013)
  • Author(s): J. Arakawa K. Watanabe J. Nagasawa M. Kubo Y. Shindo K. Kato
  • Journal Title: 2013 International Conference on Electromagnetics in Advanced Applications Volume: Proc. Pages: 524-527
  • Peer Reviewed
• [Presentation] 超音波ガイド機能による非加温体位置決め手法の実験的検討 (2015)
  • Author(s): 中村圭利、阿南大介、井関祐也、新藤康弘、加藤和夫
  • Organizer: 日本機械学会
  • Place of Presentation: 北海道大学工学部
  • Year and Date: 2015-10-10
• [Presentation] 可動型電磁シールドを有する空胴共振器の電磁界分布解析 (2015)
  • Author(s): 松下拓磨、井関祐也、新藤康弘、高橋謙治、加藤和夫
  • Organizer: 日本機械学会
  • Place of Presentation: 北海道大学工学部
  • Year and Date: 2015-10-10
• [Presentation] 超音波診断装置を用いた加温ターゲット把握機能を有する空胴共振器加温方式の基礎検討 (2015)
  • Author(s): 中村圭利，井関祐也，新藤康弘，加藤和夫
  • Organizer: 日本機械学会
  • Place of Presentation: 東京
  • Year and Date: 2015-03-20 – 2015-03-21
• [Presentation] 超音波ガイド機能を有する空胴共振器加温システムの加温特性 (2014)
  • Author(s): 中村圭利、井関祐也、新藤康利、加藤和夫
  • Organizer: 日本設計工学会
  • Place of Presentation: 東京
  • Year and Date: 2014-05-24 – 2014-05-25