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Beam condition dependence of dose monitor calibration factor for proton therapy

Research Project

Project/Area Number 25461936
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionShizuoka Cancer Center Research Institute

Principal Investigator

Kase Yuki  静岡県立静岡がんセンター(研究所), その他部局等, その他 (70455385)

Co-Investigator(Kenkyū-buntansha) YAMASHITA Haruo  静岡県立静岡がんセンター(研究所), 陽子線治療研究部, 主任研究員 (20399588)
SAKAMA Makoto  放射線医学総合研究所, 重粒子医科学センター, 研究員 (80455386)
Co-Investigator(Renkei-kenkyūsha) MIZOTA Manabu  九州国際重粒子線がん治療センター, 物理室, 室長 (60649234)
Murayama Shigeyuki  静岡県立静岡がんセンター(研究所), 陽子線治療研究部, 部長 (60231635)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords陽子線治療 / 線量モニタ / 照射野効果 / ワブラー法 / 出力係数 / モニタユニット / 線量測定
Outline of Final Research Achievements

In radiation therapy, it is necessary to preset a monitor unit in an irradiation control system to deliver a prescribed absolute dose to a reference point in the planning target volume. The purpose of this study was to develop a model-based monitor unit calculation method for proton-beam therapy. The absorbed dose at a calibration point per monitor unit had been measured for each beam-specific measurement condition before proton therapeutic irradiation.
In this study, we developed a simplified dose output model and a field-size effect calculation model to obtain the output ratio between a beam-specific dose and a reference field dose, from which a monitor unit for the proton treatment could be derived without beam-specific measurements.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 2 results) Presentation (1 results)

  • [Journal Article] Semi-analytical model for output factor calculations in proton beam therapy with consideration for the collimator aperture edge2015

    • Author(s)
      Yuki Kase, Haruo Yamashita, Makoto Sakama, Manabu Mizota, Yoshikazu Maeda, Yuji Tameshige and Shigeyuki Murayama
    • Journal Title

      Phys. Med. Biol.

      Volume: 60 Issue: 15 Pages: 5833-5852

    • DOI

      10.1088/0031-9155/60/15/5833

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A model-based analysis of a simplified beam-specific dose output in proton therapy with a single-ring wobbling system2015

    • Author(s)
      Yuki Kase, Haruo Yamashita, Masumi Numano, Makoto Sakama, Manabu Mizota, Yoshikazu Maeda, Yuji Tameshige and Shigeyuki Murayama
    • Journal Title

      Phys. Med. Biol.

      Volume: 60 Issue: 1 Pages: 359-374

    • DOI

      10.1088/0031-9155/60/1/359

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] A report of the proton machine quality assurance and quality control for wobbled-proton-beam therapy in Shizuoka Cancer Center2014

    • Author(s)
      Yuki Kase, Haruo Yamashita, Masumi Numano, Hiroshi Fuji, Shigeyuki Murayama
    • Organizer
      Computer Assisted Radiology and Surgery: 28th International Congress and Exhibition
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2014-06-25 – 2014-06-28
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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