Analysis of novel mutations in triple negative breast cancer using NGS

Research Project

Project/Area Number	25461982
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	General surgery
Research Institution	Shokei University
Principal Investigator	Kariu Toru 尚絅大学, 生活科学部, 准教授 (10412735)
Co-Investigator(Kenkyū-buntansha)	IMAMURA Takahisa 熊本大学, 大学院生命科学研究部, 准教授 (20176499)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000) Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords	乳がん / エキソーム解析
Outline of Final Research Achievements	Breast cancer is categolized into three groups according to expressions of either of ER, progesterone receptor, and HERS. To under stand and develop effective therapeutic agents against the triple negative brest cancer, we identified a correlation of the expression of anaphylatoxin receptor with cancer prognosis.