Development of intraoparative navigation systems using photodynamic imaging technique.

• Project/Area Number: 25462017
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Digestive surgery
• Research Institution: Hamamatsu University School of Medicine
• Principal Investigator: HIRAMATSU YOSHIHIRO 浜松医科大学, 医学部, 助教 (00397390)
• Co-Investigator(Kenkyū-buntansha): KONNO HIROYUKI 浜松医科大学, 医学部, 教授 (00138033) ; KIKUCHI HIROTOSHI 浜松医科大学, 医学部, 助教 (70397389)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 消化器外科学 / 内視鏡外科学 / 術中ナビゲーション / 胃外科学 / 光診断技術 / ICG

Outline of Final Research Achievements

Recent advances in imaging technique have enabled detailed preoperative diagnosis and operational simulation, leading to the further development of surgical therapies. In this study, we sought to develop a new real-time operational assistant system using optical techniques advanced in recent years. We corrected basic data and will apply them for future studies to realize practical systems, leading to success in preclinical study of fluorescent marking clip for digestive tract. We will further develop our studies for clinical application.

Research Products

• [Journal Article] Quantitative assessment of the free jejunal graft perfusion. (2015)
  • Author(s): Kamiya K, Unno N, Miyazaki S, Sano M, Kikuchi H, Hiramatsu Y, Ohta M, Yamatodani T, Mineta H, Konno H
  • Journal Title: J Surg Res Volume: 194 Issue: 2 Pages: 394-399
  • DOI: 10.1016/j.jss.2014.10.049
  • Peer Reviewed / Open Access
• [Journal Article] Collateral thermal damage to the pancreas by ultrasonic instruments during lymph node dissection in laparoscopic gastrectomy (2015)
  • Author(s): Fujita T, Ohta M, MD, Ozaki Y, Takahashi Y, Miyazaki S, Harada T, Iino I, Kikuchi H, Hiramatsu Y, Kamiya K, Konno H
  • Journal Title: Asian J Endosc Surg Volume: 8 Issue: 3 Pages: 281-288
  • DOI: 10.1111/ases.12177
  • Peer Reviewed
• [Journal Article] Three-dimensional fusion images combining CT gastrography and CT angiography for early gastric cancer: pilot experiences of preoperative simulation prior to totally laparoscopic gastrectomy. (2015)
  • Author(s): Miyazaki S, Kikuchi H, Hiramatsu Y, Ozaki Y, Iino I, Ohta M, Kamiya K, Sakaguchi T, Unno N, Konno H
  • Journal Title: Asian J Endosc Surg Volume: 8 Issue: 1 Pages: 54-58
  • DOI: 10.1111/ases.12147
  • Peer Reviewed
• [Journal Article] Laparoscopic narrow-band imaging for the diagnosis of peritoneal metastasis in gastric cancer. (2014)
  • Author(s): Kikuchi H, Kamiya K, Hiramatsu Y, Miyazaki S, Yamamoto M, Ohta M, Baba S, Konno H.
  • Journal Title: Ann Surg Oncol Volume: 21 Issue: 12 Pages: 3954-3962
  • DOI: 10.1245/s10434-014-3781-8
  • Peer Reviewed
• [Journal Article] Pancreatoduodenal artery aneurysm resulting from median arcuate ligament compression successfully treated with laparoscopic ligament section. (2014)
  • Author(s): Hiramatsu Y, Sakaguchi T, Kawabata T, Shibasaki Y, Kikuchi H, Takehara Y, Uyama I, Konno H
  • Journal Title: Asian J Endosc Surg Volume: 7 Issue: 1 Pages: 75-78
  • DOI: 10.1111/ases.12078
  • Peer Reviewed
• [Journal Article] Mesenteric paraganglioma: Report of a case. (2013)
  • Author(s): Fujita T, Kamiya K, Takahashi Y, Miyazaki S, Iino I, Kikuchi H, Hiramatsu Y, Ohta M, Baba S, Konno H
  • Journal Title: World J Gastrointest Surg Volume: 5 Issue: 3 Pages: 62-67
  • DOI: 10.4240/wjgs.v5.i3.62
  • Peer Reviewed
• [Journal Article] Usufulness of three-dimensional angiographic analysis of perigastric vessels before laparoscopic gastrectomy. (2012)
  • Author(s): Iino I, Sakaguchi T, Kikuchi H, Miyazaki S, Fujita T, Hiramatsu Y, Ohta M, Kamiya K, Ushio T, Takehira Y, Konno H.
  • Journal Title: Gastric Cancer Volume: 16 Issue: 3 Pages: 355-361
  • DOI: 10.1007/s10120-012-0194-x
  • Peer Reviewed
• [Presentation] 蛍光観察消化管マーキング用クリップの開発 (2015)
  • Author(s): 平松良浩、菊池寛利、川端俊貴、村上智洋、松本知拓、尾﨑裕介、馬場恵、太田学、神谷欣志、坂口孝宣、今野弘之
  • Organizer: 第23回日本消化器関連学会週間／第13回日本消化器外科学会大会
  • Place of Presentation: グランドプリンスホテル新高輪
  • Year and Date: 2015-10-09
• [Presentation] 食道癌切除術後結腸再建におけるグラフト血流評価の工夫 (2014)
  • Author(s): 平松良浩、神谷欣志、松本知拓、尾崎裕介、宮崎真一郎、高橋善明、飯野一郎太、藤田剛、川端俊貴、菊池寛利、太田学、坂口孝宣、今野弘之
  • Organizer: 第114回日本外科学会総会
  • Place of Presentation: 国立京都国際会館
  • Year and Date: 2014-04-03 – 2014-04-05
• [Book] 消化器外科医に必要なちょっと先いく画像診断 (2015)
  • Author(s): 平松良浩、高橋善明
  • Total Pages: 232
  • Publisher: メジカルビュー