An Experimental Study of the Safety and Efficacy of Absorbable Barbed Sutures in Laparoscopic Gastrectomy for Cancer
| Project/Area Number |
25462040
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Osaka Medical College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
内山 和久 大阪医科大学, 医学部, 教授 (80232867)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 胃癌 / 腹腔鏡下手術 / 体腔内消化管再建 / 新規縫合糸 / Barbed suture / ERASプロトコール / 回復能力強化プログラム / 胃切除術 / 術後回復能力強化プログラム / 内視鏡下手術 / 消化管縫合 / 体組成計 / 体腔内再建 / 消化管再建 |
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| Outline of Final Research Achievements |
Aim: To investigate the use of the novel barbed suture in gastrointestinal enterotomy closure. Methods: The barbed suture was used to close the entry hole for the linear stapler during intracorporeal reconstruction. Results: The enterotomy hole at 256 sites in 242 patients was closed using the barbed suture. There were no anastomosis-related complications. Conclusions: The use of the barbed absorbable suture for gastrointestinal closure is safe in laparoscopic gastrectomy.
Aim: To clarify the efficacy of the ERAS protocol in patients with gastric cancer. Results: We randomized 148 patients undergoing gastrectomy into an ERAS protocol group and a conventional protocol group. The hospital stay was significantly shorter in the ERAS protocol group. The ERAS protocol group had a significantly lower rate of postoperative complications of grade III or higher. Conclusions: The ERAS protocol is safe and efficient, and seems to improve the postoperative course of patients with gastric cancer.
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Report
(4 results)
Research Products
(8 results)
