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The development of treatment for bile duct injury and stenosis using bioabsorbable materials

Research Project

Project/Area Number 25462124
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Digestive surgery
Research InstitutionTeikyo University (2016)
Saitama Medical University (2013, 2015)

Principal Investigator

Miyazawa Mitsuo  帝京大学, 医学部, 教授 (20200165)

Co-Investigator(Kenkyū-buntansha) 合川 公康  埼玉医科大学, 医学部, 准教授 (20438823)
岡田 克也  埼玉医科大学, 医学部, 助教 (60364775)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords胆管再生 / 生体吸収性材料 / 人工胆管 / 胆管細胞 / 再生医療 / 胆管損傷 / 胆管狭窄 / 生体適合性接着剤
Outline of Final Research Achievements

Using bioabsorbable materials (bioabsorbable polymer: BAP), we studied the cure for bile duct injury, and bile duct stenosis. We developed the treatment method for bile duct injury and stenosis using BAP. With the result of this study as an article; International Surgery 2015, Vol. 100, pp. I reported it in 1408-1413, an Imperial capital medical journal (2016,39, P129-138). We tried to be able to go ahead until a clinical study within current study period, but there was a problem of the expense at the time of the problem of materials, the clinical study enforcement and was not able to be accomplished. Such materials become available for near future and hope that the low aggression in the true meaning in the biliary tract surgery domain, function preservation is accomplished.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (6 results)

All 2016 2015 2014 2013

All Journal Article (4 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 3 results,  Open Access: 3 results,  Acknowledgement Compliant: 1 results) Presentation (2 results)

  • [Journal Article] An Artificial Bile Duct Made Of Bioabsorbable Polymer: A Viable Substitute for Narrowed Portion of the Extrahepatic Bile Duct2016

    • Author(s)
      Miyazawa M, Aikawa M, Okada K,Watanabe Y, Okamoto K, Shrestha S, Yamaguchi S,Koyama I, Ikada Y,
    • Journal Title

      InternationalSurgery

      Volume: 100 Pages: 1408-1408

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 生体吸収性材料を用いて肝外胆管を再生させることが可能である2016

    • Author(s)
      宮澤光男
    • Journal Title

      帝京医学雑誌

      Volume: 39 Pages: 129-129

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] An Artificial Bile Duct Made Of Bioabsorbable Polymer: A Viable Substitute for Narrowed Portion of the Extrahepatic Bile Duct2016

    • Author(s)
      Mitsuo Miyazawa, et al.
    • Journal Title

      Int Surg.

      Volume: in press

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 肝胆膵手術における理想的胆管再建法 Tissue engineeringによる胆管再生研究からの検討(解説/特集)2015

    • Author(s)
      宮澤光男
    • Journal Title

      肝、胆、膵

      Volume: 70 Pages: 425-431

    • Related Report
      2015 Research-status Report
  • [Presentation] Tissue engineeringによる胆管再生療法の開発 ―肝胆膵外科、肝移植外科における胆管合併症減少を目指して-2014

    • Author(s)
      宮澤光男
    • Organizer
      日本外科学会
    • Place of Presentation
      京都
    • Related Report
      2013 Research-status Report
  • [Presentation] 生体吸収性材料を用いた胆管再生療法の現状と展望-人工胆管開発および生体吸収性胆道ステントの臨床応用-2013

    • Author(s)
      宮澤光男
    • Organizer
      日本消化器病週間
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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