Thin expanded polytetrafluoroethylene pulmonary valve and polytetrafluoroethylene conduit with bulging sinus
| Project/Area Number |
25462140
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Cardiovascular surgery
|
|---|
| Research Institution | Kyoto Prefectural University of Medicine |
|---|
Principal Investigator |
Yamagishi Masaaki 京都府立医科大学, 医学(系)研究科(研究院), 准教授 (40182422)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
Maeda Yoshinobu 京都府立医科大学, 大学院医学研究科, 助教 (20438203)
Miyazaki Takako 京都府立医科大学, 大学院医学研究科, 助教 (90405291)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 肺動脈弁 / 右室流出路形成 / ePTFE / 人工血管 / ポリテトラフルオロエチレン |
|---|
| Outline of Final Research Achievements |
We performed clinical use of newly developed tricuspid fan-shaped pulmonary valve using the ultra-thin ePTFE membrane and ePTEF conduit with bulging sinus for right ventricular outflow reconstruction. The diameter of the conduit was 16.4±4.0mm. The pressure gradient was 13.2±8.6mmHg in the large-diameter group (more than 18mm) and 16.3±10.4mmHg in the small diameter group (16mm or less). It was suggested that the ultra-thin ePTFE membrane valve effective technology for preventing stenosis. Pulmonary regurgitation significantly increased in a large-diameter (22, 24mm) conduit.
|
Report
(3 results)
Research Products
(14 results)
