Surgical Strategy for Aortic Arch Reconstruction after Norwood Procedure based on a Virtual Operation with Numerical Flow Analysis
| Project/Area Number |
25462145
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular surgery
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| Research Institution | Wakayama Medical University (2015)
Kitasato University (2013) |
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Principal Investigator |
Oka Norihiko 和歌山県立医科大学, 医学部, 講師 (20328420)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 血流解析 / 先天性心疾患 / 数値流体シミュレーション / 画像診断 / 血流可視化 / 心機能 / エネルギー損失 / 先天性大動脈疾患 |
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| Outline of Final Research Achievements |
In the first year, using vector flow mapping (VFM) based on echocardiography, the flow in a reconstructed aortic arch after Norwood operation was analyzed as a pilot data. We validated that the result of VFM analysis was compatible with that of computational fluid dynamics (CFD). In the second year, we validated the reliability of VFM analysis by comparing the date with 4DMRI analysis. Further data accumulation was achieved and reached up to 24 cases in this year. By analyzing the data, we found that the reconstructed aortic arch with more than 70 Pascal of shear stress would affect patients’ cardiac function and requires reoperation. In the third year, we confirmed that the reoperation for the aortic arch with more than 70 of shear stress Pascal certainly reduces energy loss that may improve the patients’ cardiac function in a long term.
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Report
(3 results)
Research Products
(14 results)
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[Journal Article] Impact of the entry site on late outcome in acute Stanford type B aortic dissection†.2015
Author(s)
Kitamura T, Torii S, Oka N, Horai T, Itatani K, Yoshii T, Nakamura Y, Shibata M, Tamura T, Araki H, Matsunaga Y, Sato H, Miyaji K
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Journal Title
European Journal of Cardiothoracic Surgery
Volume: 48
Issue: 5
Pages: 655-661
DOI
Related Report
Peer Reviewed
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[Journal Article] Seventeen-month-long paracorporeal biventricular mechanical support as a bridge to transplantation for severe dilated cardiomyopathy2015
Author(s)
Kitamura T, Torii S, Oka N, Horai T, Itatani K, Yoshii T, Nakamura Y, Shibata M, Tamura T, Araki H, Matsunaga Y, Miyaji K.
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Journal Title
J Artif Organs
Volume: 18
Issue: 1
Pages: 92-94
DOI
Related Report
Peer Reviewed
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[Journal Article] Effect of the Neutrophil Elastase Inhibitor Sivelestat on Perioperative Inflammatory Response After Pediatric Heart Surgery with Cardiopulmonary Bypass: A Prospective Randomized Study. Artif Organs.2013
Author(s)
Kohira S, Oka N, Inoue N, Itatani K, Hanayama N, Kitamura T, Fujii M, Takeda A, Oshima H, Tojo K, Yoshitake S, Miyaji K.
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Journal Title
Artificial Organs
Volume: 37
Pages: 1027-33
Related Report
Peer Reviewed
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[Book] Advances in Hemodynamics Research2015
Author(s)
Shohei Miyazaki, Keiichi Itatani, Sachi Koyama, Kouki Nakashima, Tetsuya Horai, Norihiko Oka, Tadashi Kitamura and Kagami Miyaji
Total Pages
302
Publisher
Nova Science Publishers
Related Report
