Prospective study of patients with abdominal aortic aneurysm focused on diabetes
| Project/Area Number |
25462157
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular surgery
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| Research Institution | Kansai Medical University (2015-2016)
Tohoku University (2013) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
後藤 均 東北大学, 医学系研究科, 准教授 (00400333)
佐藤 成 東北大学, 医学系研究科, 講師 (20250764)
赤松 大二朗 東北大学, 大学病院, 助教 (40420012)
橋本 宗敬 東北大学, 大学病院, 助教 (10375040)
清水 拓也 東北大学, 医学系研究科, 大学院非常勤講師 (70579755)
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| Research Collaborator |
TAJIMA Yuta
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 腹部大動脈瘤 / 拡大速度 / 糖尿病 / アンギオテンシンレセプター拮抗薬 / Ｄダイマー / 小径 / 観察研究 |
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| Outline of Final Research Achievements |
We prospectively followed up 81 patients with small abdominal aortic aneurysm and examined a factor associated with aneurysm progression. We foucus on several reports about negative relation with dibates and anerusym expansion. However, no significant association was noted betweeen them in our study. Intial aortic diameter, higher serum D-dimer, lower serum total protein were positively associated with anerysym expansion. Whereas, medication with angiotensin receptor blocker was negatively associated with aneurysm expansion. Further investigation about those association might lead to novel medication against abdominal aortic aneurysm progression.
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Report
(4 results)
Research Products
(2 results)
