| Project/Area Number |
25462186
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Respiratory surgery
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
USUDA Katsuo 金沢医科大学, 医学部, 教授 (00324046)
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| Co-Investigator(Kenkyū-buntansha) |
UEDA Yoshimichi 金沢医科大学, 医学部, 教授 (50271375)
MATOBA Munetaka 金沢医科大学, 医学部, 教授 (90288308)
SAGAWA Motoyasu 金沢医科大学, 医学部, 教授 (70292274)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | MR拡散強調画像 / PET-CT / 肺癌 / 縦隔腫瘍 / 画像診断 / 肺腫瘤状陰影 / 肺門縦隔リンパ節 / 診断精度 / EGFR遺伝子変異 / ground glass opacity / 拡散強調画像 |
|---|
| Outline of Final Research Achievements |
Diffusion-weighted imaging (DWI) could detect significantly smaller metastatic lymph nodes than by PET-CT. It was a reason why DWI presented a significantly higher accuracy than that of PET-CT. DWI had more potential than PET-CT in assessing pulmonary lesions. For recurrence or metastasis from lung cancer, the detection rate of DWI was significantly higher than that of CT, but not significantly higher than that of PET-CT. For mediastinal tumors, the sensitivity (100%) of DWI is not significantly higher than that (93.8%) of PET-CT, the specificity (83.3%) of DWI was not significantly higher than that (66.7%) of PET-CT, and the accuracy (92.9%) of DWI was not significantly higher than that (82.1%) of PET-CT. For multiple hilar and mediastinal lymph nodes (MHMLN) with FDG accumulation, specificity and accuracy of DWI were significantly higher than those of PET-CT. Evaluation by DWI for patients with MHMLN with FDG accumulation was useful for distinguishing benignity and malignancy.
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