Fundamental research about the MR intervention without radiation exposure

Research Project

Project/Area Number	25462216
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Neurosurgery
Research Institution	Kobe University
Principal Investigator	FUJITA ATSUSHI 神戸大学, 医学(系)研究科(研究院), 助教 (60379360)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000) Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000) Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000) Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	MR imaging / catheter tracking / interventional radiology / 放射線被曝 / インターベンション / 血管内治療 / 磁気共鳴画像 / インターベンショナルラジオロジー（IVR） / 医療被爆 / 磁気共鳴装置 / MR fluoroscopy
Outline of Final Research Achievements	During catheter intervention, we are now using X-ray fluoroscopic images to guide various devices to the pathologic lesion. As the number of catheter interventions have been increasing, the patient’s radiation exposure also continue to grow. If we can guide these devices by magnetic resonance fluoroscopy, we would achieve the ideal treatment without radiation exposure for patients. In this study, we investigated the visibility of both the microcatheter and microguidewire by various imaging. Among these images, fully refocused steady-state free precession (SSFP) was thought to be feasible to the catheter tracking with good contrast-noise ratio (CNR). For fluoroscopic imaging, we also investigated the visibility and trackability of these devices. While SSFP imaging could track the microcatheter with acceptable CNR, it was difficult to track the microguidewire with acceptable visibility.