| Project/Area Number |
25462246
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurosurgery
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
AOKI Hiroshi 新潟大学, 脳研究所, 非常勤講師 (30515771)
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| Research Collaborator |
TAKAO Tetsuro
HIRAISHI Tetsuya
SATO Keisuke
SATO Yosuke
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | NIRS / cortico-cortical network / imonitoring / cortical stimulation / epilepsy surgery / monitoring / functional mapping / language system / Broca / Wernicke / MEP |
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| Outline of Final Research Achievements |
We developed novel probes of near-infrared spectroscopy (NIRS) to measure regional cerebral blood flow (rCBF) from brain surfaces. In a patient with brain tumor, stimulation to the supplementary motor area, where the seizure onset zone existed, lead to increase in rCBF in the primary motor area by intraoperative NIRS. In the other patients with brain tumor, stimulation to the inferior frontal gyrus in the left side resulted in increase in rCBF in the superior temporal gyrus. These results suggest that intraoperative NIRS could visualize cortico-cortical network system. In future, intraoperative NIRS likely evaluates the language system as intraopeartive monitoring.
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