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Analysis of pathomechanism of lumbar spondylolsis

Research Project

Project/Area Number 25462294
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionThe University of Tokushima

Principal Investigator

SAKAI Toshinori  徳島大学, 大学院医歯薬学研究部, 特任准教授 (80403731)

Co-Investigator(Kenkyū-buntansha) TAKATA Yoichiro  徳島大学, 大学院医歯薬学研究部, 特任講師 (20420549)
KATOH Shinsuke  徳島大学, 病院, 教授 (30243687)
NISHISHO Toshihiko  徳島大学, 大学院医歯薬学研究部, 講師 (40444723)
HIGASHINO Kosaku  徳島大学, 病院, 特任准教授 (80380129)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords腰椎分離症 / 血管支配 / 腰仙椎移行部 / 発生原因 / 疲労骨折 / 血管 / 関節突起間部 / 潜在性二分脊椎 / 腰仙椎
Outline of Final Research Achievements

We had mainly three results during the study period. (1) Lumbar spondylolysis in elementary school age children was frequently identified as a terminal-stage bone defect at L5. The defect was not necessarily related to history of athletic activity and was sometimes asymptomatic. In addition, L5 spondylolysis was frequently concomitant with spina bifida occulta, suggesting a genetic predisposition. (2) From L1 to L4, each segmental artery was identified bilaterally in more than 90% of subjects, but it was identified in less than 10% of patients at L5. Four main patterns of vascular supply to the posterior element of L5 by the two arteries were identified, and approximately 50% of subjects had a regular vascular pattern as described in the textbook. (3) Among of those four patterns above, lumbar spondylolysis were significantly associated with one variation.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (12 results)

All 2016 2015 2014

All Journal Article (2 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (10 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Variation in arterial supply to the lower lumbar spine.2016

    • Author(s)
      Fumitake Tezuka, Toshinori Sakai, Toshihiko Nishisho, Yoichiro Takata, Kosaku Higashino, Shoichiro Takao, Masafumi Harada, Koichi Sairyo.
    • Journal Title

      Eur Spine J

      Volume: Feb 9. Issue: 12 Pages: 4181-4187

    • DOI

      10.1007/s00586-016-4427-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Characteristics of lumbar spondylolysis in elementary school age children.2016

    • Author(s)
      Toshinori Sakai, Yuichiro Goda, Fumitake Tezuka, Yoichiro Takata, Kosaku Higahino, Masahiro Sato, Yasuyoshi Mase, Akihiro Nagamachi, Koichi Sairyo.
    • Journal Title

      Eur Spine J.

      Volume: Feb;25(2) Issue: 2 Pages: 602-606

    • DOI

      10.1007/s00586-015-4029-4

    • NAID

      40021251541

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] 腰仙椎移行部の血管分布からみたL5分離症の発生要因の検討2015

    • Author(s)
      酒井紀典 手束文威 西庄俊彦 阿部光伸 高田洋一郎 東野恒作 西良浩一
    • Organizer
      第30回日本整形外科学会基礎学術集会
    • Place of Presentation
      富山国際会議場(富山市)
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] 腰椎分離症の発生要因の検討  -腰仙椎移行部の血管分布とL5分離症との関連性について-2015

    • Author(s)
      酒井紀典 手束文威 西庄俊彦 阿部光伸 高田洋一郎 東野恒作 西良浩一
    • Organizer
      第41回日本整形外科スポーツ医学会学術集会
    • Place of Presentation
      ウェスティン都ホテル京都(京都市)
    • Year and Date
      2015-09-11
    • Related Report
      2015 Annual Research Report
  • [Presentation] Characteristics of Lumbar Spondylolysis in Elementary School Age Children2015

    • Author(s)
      Toshinori Sakai, Yuichiro Goda, Fumitake Tezuka, Yoichiro Takata, Kosaku Higashino, Koichi Sairyo.
    • Organizer
      SPINE ACROSS THE SEA
    • Place of Presentation
      BIG Island, Hawai, USA
    • Year and Date
      2015-07-26
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Characteristics of Lumbar Spondylolysis in Elementary School Age Children2015

    • Author(s)
      Toshinori Sakai, Yuichiro Goda, Fumitake Tezuka, Yoichiro Takata, Kosaku Higashino, Masahiro Sato, Yasuyoshi Mase, Koichi Sairyo.
    • Organizer
      42nd International Society for the Study of the Lumbar Spine Annual Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2015-06-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Lumbar spondylolysis in elementary school children2015

    • Author(s)
      Toshinori Sakai, Yuichiro Goda, Fumitake Tezuka, Yoichiro Takata, Kosaku Higashino, Koichi Sairyo
    • Organizer
      第88回日本整形外科学会学術総会
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] 小学生以下の子供に発症した腰椎分離症2015

    • Author(s)
      酒井紀典 合田有一郎 手束文威 高田洋一郎 東野恒作 佐藤正裕  間瀬泰克 西良浩一
    • Organizer
      第44回日本脊椎脊髄病学会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] L5分離症と下位腰椎血管分布の関連2015

    • Author(s)
      手束文威 酒井紀典 西庄俊彦 高田洋一郎 東野恒作 西良浩一
    • Organizer
      第124回中部日本整形外科災害外科学会
    • Place of Presentation
      ホテル日航金沢(金沢市)
    • Year and Date
      2015-04-10
    • Related Report
      2015 Annual Research Report
  • [Presentation] Analysis of vascular patterns for the posterior elements of the lower lumbar spine2014

    • Author(s)
      Toshinori Sakai, Fumitake Tezuka, Toshihiko Nishisho, Yoichiro Takata, Kosaku Higashino, Shinsuke Katoh, Shoichiro Takao, Masafumi Harada, Koichi Sairyo
    • Organizer
      第43回日本脊椎脊髄病学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Related Report
      2013 Research-status Report
  • [Presentation] 下位腰椎後方要素の血管分布の解析2014

    • Author(s)
      手束 文威,酒井 紀典,西庄 俊彦,高田 洋一郎,東野 恒作, 加藤 真介,高尾 正一郎,原田 雅史,西良 浩一
    • Organizer
      第87回日本整形外科学会学術総会
    • Place of Presentation
      神戸国際展示場(兵庫県神戸市)
    • Related Report
      2013 Research-status Report
  • [Presentation] Analysis of vascular patterns for the posterior elements of the lower lumbar spine2014

    • Author(s)
      Toshinori Sakai, Fumitake Tezuka, Toshihiko Nishisho, Yoichiro Takata, Kosaku Higashino, Shinsuke Katoh, Shoichiro Takao, Masafumi Harada, Koichi Sairyo
    • Organizer
      The 41st annual meeting of the International Society for the Study of the Lumbar Spine
    • Place of Presentation
      Yonsei University Health System Severance Hospital(韓国ソウル)
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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