| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Adolescent Idiopathic Scoliosis, which dramatically worsens in the adolescent period, is characterized by the features of right thoracic scoliosis. To date, a variety of pathogenic factors have been proposed as a cause of idiopathic scoliosis, however, the cause remains unclear. One of the factors limiting elucidating the treatment method of idiopathic scoliosis has been the lack of a relevant animal model. We found that the anteroposterior chest dimension in patients with thoracic scoliosis was significantly smaller than that in normal people. By applying no surgical orthosis, we could established mouse model of scoliosis. In the future, we could develop a new concept orthosis or a new minimal invasive method for the treatment of scoliosis. Additionally, we found a new sagittal parameter to estimate the pelvic tilt, which is important for daily practice.
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