| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
When bacteria form biofilm on biomaterial surface, chemo-therapy with antibiotics is difficult, and surgeries for implant-related infection are required. We evaluated the efficacy of mechanical charactors of biomaterial and environmental factors inhibiting biofilm formation. The smooth and hydrophobic surface of biomaterial obstructed bacterial adherence. In addition to that, biofilm formation was inhibited in albumin rich environment at lower temperature. These finding will help us to prevent a postoperative implant-related infection and to treat the suffered patients.
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