Drilling effect of the regeneration of fibrocartilage at the tendon to bone insertion after rotator cuff repair

Research Project

Project/Area Number	25462348
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Orthopaedic surgery
Research Institution	Kyoto Prefectural University of Medicine
Principal Investigator	Toru Morihara 京都府立医科大学, 医学(系)研究科(研究院), 准教授 (90336735)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000) Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords	腱板修復 / 骨髄由来細胞 / 肩 / 腱板
Outline of Final Research Achievements	The purpose of this study is to analyze the kinetics of bone marrow-derived cells involved in the healing process of rotator cuff repair at the tendon to bone insertion. Mesenchymal cells infiltrated and fibrocartilage layer regeneration was observed in group, drilling into the footprint and preserving the fibrous cartilage tissues besides rotator cuff repair. Drilling into the footprint and preserving the fibrocartilage tissue can improve tissue repair at the repaired tendon to bone insertion following rotator cuff repair.