The neuroprotective effects of a combination of alpha2 agonist and KATP channel opener after transient forebrain ischemia i rats
| Project/Area Number |
25462396
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Anesthesiology
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| Research Institution | Akita University |
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Principal Investigator |
SATO KOJI 秋田大学, 医学部, 助教 (80333938)
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| Co-Investigator(Kenkyū-buntansha) |
MASAKI YOKO 秋田大学, 医学(系)研究科(研究院) (30125744)
NISHIKAWA TOSHIAKI 秋田大学, 医学(系)研究科(研究院) (50156048)
NAKAJIMA MAIKO 秋田大学, 医学部, 助教 (50534096)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 一過性前脳虚血 / ニコランジル / デクスメデトミジン |
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| Outline of Final Research Achievements |
The combination of dexmedetomidine and nicorandil provided comparable short-term neuroprotection with either of the two therapies alone after transient forebrain ischemia in rats.
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Report
(3 results)
Research Products
(4 results)
