| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Hepatic ischemia is sometimes fatal but it is yet to be well established it non-invasively. However Near-infrared spectroscopy (NIRS) is useful for assessing the oxygenation state in the brain. At present it is not clear whether NIRS provides reliable values on the tissue oxygenation of various organs . The aim of this study was to investigate whether changes in hepatic oxygenation can be detected by one of new NIRS methods (TRS). In the exam using another rabbit, TRS probe was placed on the abdominal skin above the liver surface. During balloon inflation, total Hb concentration gradually increased. It indicated liver congestion was well constructed. As total Hb increased, deoxy-Hb gradually increased too. This means TRS detected the change of liver ischemia. We need reference to confirm TRS can detect not the oxygenation of the skin, but that of the liver. TRS can measure the the change of oxygenation in the liver ischemia percutaneously from the skin.
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