| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
A thrombus and arteriosclerosis are the severe clinical condition of the life. We analyzed urinary stones in detail, and confirmed that protein Z which suppresses blood clotting was included in a high frequency in the urinary stone and examined its role in the formation of urinary calculus. As a result, protein Z was detected in urinary stones that was composed of calcium oxalate monohydrate and it was found that protein Z made crystal of calcium oxalate monohydrate increase on the lipid membrane. Protein Z is expected to suppress blood clotting, but it is considered that protein Z has different role on generation of urinary calculus.
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