|Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|Outline of Final Research Achievements
In this study, we performed comprehensive gene expression analysis of the contra-lesional cerebrum of neonatal ischemic-hypoxic encephalopathy animal model at acute phase. The results suggest that 1 hour after lesioning, inflammatory responses are induced, and that induced inflammatory reactions continue at 24 hour after lesioning. Furthermore, neuropathy progression is suggested at both 1 hour and 24 hour after lesioning. From these results, we concluded that the contra-lesional hemisphere of neonatal ischemic-hypoxic encephalopathy animal model is important subject of investigation.